Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | NOS1 | P29475 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14676716 | 0.91 | NOS1 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11439040 | 0.89 | NOS1 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5575000 | 0.87 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8202595 | 0.86 | NOS1 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11439050 | 0.85 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1170413 | 0.84 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11451227 | 0.82 | NOS1 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17434763 | 0.82 | NOS1 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5666794 | 0.80 | NOS1 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL163065 | 0.80 | NOS1 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170226259-A1 | Ordered Architectures in Acrylic Polymers | AVERY DENNISON CORPORATION | 2017-08-10 | — | — | US | disclosed |
| US-9644063-B2 | Ordered architectures in acrylic polymers | AVERY DENNISON CORPORATION (US) | 2017-05-09 | — | — | US | disclosed |
| US-9255198-B2 | Water swellable polymer materials comprising particulate core and water swellable R.A.F.T polymer shell | THE UNIVERSITY OF SYDNEY (AU) | 2016-02-09 | — | — | US | disclosed |
| US-8796359-B2 | Polymer product and interfacial polymerisation process using raft agent | THE UNIVERSITY OF SYDNEY (AU) | 2014-08-05 | — | — | US | disclosed |
| US-8779029-B2 | Polymer product and interfacial polymerisation process using raft agent | THE UNIVERSITY OF SYDNEY (AU) | 2014-07-15 | — | — | US | disclosed |
| EP-2643414-A2 | PROCESS FOR PRODUCING POLYMER-FUNCTIONALIZED FILLER PARTICLES | Continental Reifen Deutschland GmbH (DE) | 2013-10-02 | — | — | EP | disclosed |
| US-20130087736-A1 | WATER SWELLABLE POLYMER MATERIALS | THE UNIVERSITY OF SYDNEY (AU) | 2013-04-11 | — | — | US | disclosed |
| US-20130059971-A1 | Ordered Architectures in Acrylic Polymers | AVERY DENNISON CORPORATION (US) | 2013-03-07 | — | — | US | disclosed |
| WO-2012069403-A2 | PROCESS FOR PRODUCING POLYMER-FUNCTIONALIZED FILLER PARTICLES | CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) | 2012-05-31 | — | — | WO | disclosed |
| US-20120128743-A1 | POLYMER PARTICLES | THE UNIVERSITY OF SYDNEY (AU) | 2012-05-24 | — | — | US | disclosed |
| US-20120123057-A1 | METHOD FOR PREPARING OLEFIN-BASED SEGMENTED COPOLYMERS | Hong, Sung Chul (KR) | 2012-05-17 | — | — | US | disclosed |
| US-20110196088-A1 | POLYMER PRODUCT AND INTERFACIAL POLYMERISATION PROCESS USING RAFT AGENT | THE UNIVERSITY OF SYDNEY (AU) | 2011-08-11 | — | — | US | disclosed |
| US-20110118372-A1 | Acrylic Polymers Having Controlled Placement of Functional Groups | AVERY DENNISON CORPORATION (US) | 2011-05-19 | — | — | US | disclosed |
| US-7718342-B2 | Polymers, resist compositions and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-05-18 | — | — | US | disclosed |
| US-20100048750-A1 | VESICULATED POLYMER PARTICLES | THE UNIVERSITY OF SYDNEY (AU) | 2010-02-25 | — | — | US | disclosed |
| US-20090258979-A1 | POLYMER PRODUCT AND INTERFACIAL POLYMERISATION PROCESS USING RAFT AGENT | THE UNIVERSITY OF SYDNEY (AU) | 2009-10-15 | — | — | US | disclosed |
| US-20070148594-A1 | Polymers, resist compositions and patterning process | SHIN-ETSU CHEMICAL CO., LTD. | 2007-06-28 | — | — | US | disclosed |
| US-4197311-A | CONTROL OF INSECTS AND ACARINA, ALSO OVICIDAL USE OF DITHIOCARBONATES | AMERICAN CYANAMID COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120128743-A1 | POLYMER PARTICLES | ELOC, EPN1, FASN | HDAC3 4524/4885HDAC4 4759/4885HDAC1 4632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.