Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 4/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290225 | 1.00 | BHMT (0.37) | BHMTARG1ARG2NOS2NOS1 | |
| SCHEMBL2250779 | 0.89 | TDP1 (0.33) | ALOX15EYA2APPACETDP1 | |
| SCHEMBL2250788 | 0.89 | TDP1 (0.33) | ALOX15EYA2APPACETDP1 | |
| Cystine SCHEMBL7564898 | 0.80 | ARG1 (0.48) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL7564905 | 0.80 | ARG1 (0.48) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL8159939 | 0.79 | SLC1A2 (0.40) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL2981869 | 0.78 | GLUL (0.37) | BHMTARG1ARG2NOS2NOS1 | |
| SCHEMBL2981882 | 0.78 | GLUL (0.37) | BHMTARG1ARG2NOS2NOS1 | |
| Cystine SCHEMBL10225 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 | |
| Cystine SCHEMBL10224 | 0.78 | PTGS1 (0.50) | ARG1ARG2NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709612-B2 | Metal chelating compositions for protein purification, detection or binding | SIGMA-ALDRICH CO. (US) | 2010-05-04 | — | — | US | disclosed |
| US-20060148090-A1 | Metal chelating compositions for protein purification, detection or binding | SIGMA-ALDRICH CO. (US) | 2006-07-06 | — | — | US | disclosed |
| US-7033520-B2 | Metal chelating compositions for protein purification, detection or binding | SIGMA-ALDRICH CO. (US) | 2006-04-25 | — | — | US | disclosed |
| EP-1627683-A2 | Metal chelating compositions | Sigma Aldrich Company (US) | 2006-02-22 | — | — | EP | disclosed |
| EP-1276716-B1 | METAL CHELATING COMPOSITIONS | SIGMA ALDRICH CO (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20040092031-A1 | Metal chelating compositions for protein purification, detection or binding | SIGMA - ALDRICH CO. | 2004-05-13 | — | — | US | disclosed |
| US-6623655-B1 | Nitrilotriacetic acid derivatives; improved specificity and stability; protein purification, detection and/or binding | SIGMA-ALDRICH CO. | 2003-09-23 | — | — | US | disclosed |