Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967503 | 0.98 | TDP1 (0.53) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL27996450 | 0.95 | TDP1 (0.52) | TDP1MEN1KMT2AGAAMAOA | |
| Hydroxyamine SCHEMBL10630230 | 0.93 | TDP1 (0.50) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL14717853 | 0.89 | TDP1 (0.47) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL28706944 | 0.87 | TDP1 (0.46) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL11168531 | 0.86 | MAOA (0.46) | TDP1MEN1KMT2AGAAMAOA | |
| Dichloroacetic Acid SCHEMBL28652128 | 0.84 | MEN1 (0.53) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL27822268 | 0.84 | MEN1 (0.45) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL9476914 | 0.83 | EPHX1 (0.41) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL3984277 | 0.83 | TDP1 (0.46) | TDP1MEN1KMT2AGAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937152-B2 | Non-selective somatostatin analogues | ITALFARMACO SPA (IT) | 2015-01-20 | — | — | US | disclosed |
| EP-2225271-B1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2013-07-31 | — | — | EP | disclosed |
| US-20100323964-A1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2010-12-23 | — | — | US | disclosed |
| EP-2225271-A2 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO S.p.A. (IT) | 2010-09-08 | — | — | EP | disclosed |
| US-7718157-B1 | Targeted lipid particles | BAKER TERENCE SEWARD | 2010-05-18 | — | — | US | disclosed |
| WO-2009071460-A2 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2009-06-11 | — | — | WO | disclosed |
| EP-2067786-A1 | Novel non selective analogs of somatostatin | ITALFARMACO S.p.A. (IT) | 2009-06-10 | — | — | EP | disclosed |
| US-7531676-B2 | Lipids | CELLTECH R & D LIMITED (GB) | 2009-05-12 | — | — | US | disclosed |
| US-20060148761-A1 | Lipids | CELLTECH R & D LIMITED | 2006-07-06 | — | — | US | disclosed |
| US-20040024220-A1 | Lipids | CELLTECH R & D LIMITED | 2004-02-05 | — | — | US | disclosed |
| US-6583301-B1 | Bipolar; form complexes with polyanions; delivering bioactive substances such as nucleic acids to cells in vitro and in vivo | CELLTECH R & D LIMITED (GB) | 2003-06-24 | — | — | US | disclosed |
| EP-1070047-A2 | LIPIDS | Celltech Chiroscience Limited (GB) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052858-A2 | LIPIDS | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024220-A1 | Lipids | PHOSPHO1, FABP7, MBOAT7 | TDP1 1253/4885MEN1 1304/4885KMT2A 3580/4885 |
| US-20060148761-A1 | Lipids | PHOSPHO1, FABP7, MBOAT7 | TDP1 1253/4885MEN1 1304/4885KMT2A 3580/4885 |
| US-20100323964-A1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | SSTR4, SSTR1, SSTR3 | TDP1 4282/4885MEN1 115/4885KMT2A 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.