SCHEMBL14717853

SCHEMBL14717853

CCNC(=O)OC(C)(C)C.F[B-](F)(F)F.F[B-](F)(F)F.F[B-](F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
CTSK P43235 5/20 0.42
CTSS P25774 3/20 0.42
CAPN1 P07384 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
CA1 P00915 4/20 0.40
CA12 O43570 3/20 0.40
CA7 P43166 2/20 0.40
CA14 Q9ULX7 1/20 0.40
APLNR P35414 1/20 0.40
CA2 P00918 3/20 0.39
CA9 Q16790 2/20 0.39
EPHX1 P07099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28706944 0.98 TDP1 (0.46) TDP1MEN1GAAKMT2ACTSK
SCHEMBL967503 0.91 TDP1 (0.53) TDP1MEN1GAAKMT2ACTSK
SCHEMBL27996450 0.89 TDP1 (0.52) TDP1MEN1GAAKMT2ACTSK
Ammonia Solution, Strong SCHEMBL3290266 0.89 TDP1 (0.52) TDP1MEN1GAAKMT2ACTSK
Hydroxyamine SCHEMBL10630230 0.87 TDP1 (0.50) TDP1MEN1GAAKMT2ACTSK
SCHEMBL27224646 0.82 TDP1 (0.46) TDP1MEN1GAAKMT2ACTSK
SCHEMBL20489210 0.80 TDP1 (0.44) TDP1MEN1GAAKMT2ACTSK
SCHEMBL11168531 0.80 MAOA (0.46) TDP1MEN1GAAKMT2ACTSK
SCHEMBL15715984 0.79 TDP1 (0.47) TDP1MEN1GAAKMT2ACTSK
Dichloroacetic Acid SCHEMBL28652128 0.79 MEN1 (0.53) TDP1MEN1GAAKMT2ACTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087635-A1 DIHYDRO BENZOXAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
US-20250270173-A1 PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2025-08-28 US disclosed
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 WO disclosed
US-20240208992-A1 MACROCYCLES AS CFTR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-27 US disclosed
WO-2024112830-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2024-05-30 WO disclosed
US-20240057606-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2024-02-22 US disclosed
US-20240025883-A1 PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2024-01-25 US disclosed
EP-4298092-A1 NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2024-01-03 EP disclosed
US-11839613-B2 Pyrimidine derivatives as PGE2 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2023-12-12 US disclosed
WO-2023205116-A1 PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2023-10-26 WO disclosed
US-20140274688-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2014-09-18 US disclosed
US-20140275524-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2014-09-18 US disclosed
US-20140275047-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2014-09-18 US disclosed
US-20140256739-A1 METHOD OF TREATMENT GLAXOSMITHKLINE LLC 2014-09-11 US disclosed
EP-2773754-A1 METHOD OF TREATMENT Glaxosmithkline Intellectual Property (No. 2) Limited (GB) 2014-09-10 EP disclosed
US-20130345200-A1 INDOLES GLAXOSMITHKLINE LLC (US) 2013-12-26 US disclosed
US-8536179-B2 Indoles GLAXOSMITHKLINE LLC (US) 2013-09-17 US disclosed
WO-2013067296-A1 METHOD OF TREATMENT GLAXOSMITHKLINE INTELLECTUAL PROPERTY (No 2) LIMITED (GB) 2013-05-10 WO disclosed
EP-2566327-A1 INDOLES GlaxoSmithKline LLC (US) 2013-03-13 EP disclosed
US-20130053397-A1 INDOLES GLAXOSMITHKLINE LLC 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140275524-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO ACHE, DDT, MLYCD TDP1 649/4885MEN1 832/4885GAA 807/4885
US-20140275047-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO ACHE, DDT, MLYCD TDP1 649/4885MEN1 832/4885GAA 807/4885
US-11839613-B2 Pyrimidine derivatives as PGE2 receptor modulators PTGER1, PTGER4, PTGER2 TDP1 2322/4885MEN1 4485/4885GAA 4879/4885
US-20240057606-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO ACHE, DDT, MLYCD TDP1 496/4885MEN1 565/4885GAA 691/4885
US-20240025883-A1 PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES GPR17, GPR27, GPR119 TDP1 3673/4885MEN1 2067/4885GAA 1897/4885
US-20140256739-A1 METHOD OF TREATMENT EZH1, EZH2, SUV39H2 TDP1 3689/4885MEN1 3219/4885GAA 2331/4885
US-20240208992-A1 MACROCYCLES AS CFTR MODULATORS CFTR, PKD1, ARRB1 TDP1 4270/4885MEN1 1575/4885GAA 2994/4885
US-20140274688-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO ACHE, DDT, MLYCD TDP1 649/4885MEN1 832/4885GAA 807/4885
US-20250270173-A1 PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS GRIN2C, HTR1A, GRIA4 TDP1 1309/4885MEN1 4101/4885GAA 2335/4885
US-20130345200-A1 INDOLES IDO1, IDO2, INMT TDP1 1357/4885MEN1 783/4885GAA 3880/4885
US-20130053397-A1 INDOLES IDO1, IDO2, INMT TDP1 1417/4885MEN1 795/4885GAA 3907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.