Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Demannose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL537703 | 1.00 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL7958057 | 1.00 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL3872401 | 1.00 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Galactose SCHEMBL6900501 | 1.00 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL27994608 | 0.98 | LMNA (0.48) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL9938071 | 0.98 | LMNA (0.48) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL2341216 | 0.98 | LMNA (0.48) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL28146511 | 0.95 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL1681820 | 0.94 | LMNA (0.44) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL11509811 | 0.94 | PDE4A (0.47) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925001-B | Ta2O5NiO composite hollow nanosphere material and preparation method and application thereof | 浙江大学山东工业技术研究院 | 2024-06-04 | — | — | CN | claimed |
| CN-116874928-A | High-strength antibacterial, antistatic and ultraviolet-resistant hollow plastic plate and preparation method thereof | 青岛奥海瑞泰实业有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-115109468-B | Multifunctional water-based damping paint and preparation method thereof | 浙江工业大学 | 2023-09-08 | — | — | CN | claimed |
| CN-113697794-B | Method for preparing dendritic superfine hydrothermal carbon by slow temperature control method, prepared hydrothermal carbon adsorption ball and application | 广东工业大学 | 2023-08-08 | — | — | CN | claimed |
| CN-116375112-A | Ta2O5/NiO@Ti3C2Tx flaky nanoflower material and preparation method thereof | 浙江大学山东工业技术研究院 | 2023-07-04 | — | — | CN | claimed |
| CN-115925001-A | Ta 2 O 5 /NiO composite hollow nanosphere material and preparation method and application thereof | 浙江大学山东工业技术研究院 | 2023-04-07 | — | — | CN | claimed |
| CN-115873578-A | Foaming agent composition for sensitive heavy oil reservoir and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-115410657-A | Method for predicting mycelium concentration, ethanol concentration and glucose concentration time sequence in fuel ethanol fermentation process | 华东理工大学 | 2022-11-29 | — | — | CN | claimed |
| CN-115363236-A | Preparation method of tobacco flavor with sour and sweet flavors and application of tobacco flavor | 湖北中烟工业有限责任公司 | 2022-11-22 | — | — | CN | claimed |
| CN-115380115-A | Method for producing glucose and method for producing ethanol | 本田技研工业株式会社 | 2022-11-22 | — | — | CN | claimed |
| CN-102076804-B | Adhesive composition, polarizing plate, and liquid crystal display | LG CHEMICAL LTD | 2013-05-29 | — | — | CN | claimed |
| CN-102891315-A | Method for preparing lithium iron phosphate serving as cathode active material of lithium ion secondary battery | ORIGINAL ENERGY TECHNOLOGY BEIJING INC | 2013-01-23 | — | — | CN | claimed |
| EP-2461797-A1 | PROCESS FOR PREPARATION OF OVER-THE-COUNTER GELATIN OR PECTIN-BASED DRUG DELIVERY | 7267207 Canada Limited Corporation (CA) | 2012-06-13 | — | — | EP | claimed |
| US-8078334-B2 | Unobtrusive system and method for monitoring the physiological condition of a target user of a vehicle | 1A SMART START LLC | 2011-12-13 | — | — | US | claimed |
| CN-102076804-A | Adhesive composition, polarizing plate, and liquid crystal display | LG CHEMICAL LTD | 2011-05-25 | — | — | CN | claimed |
| WO-2011014960-A1 | PROCESS FOR PREPARATION OF OVER-THE-COUNTER GELATIN OR PECTIN-BASED DRUG DELIVERY | 7267207 CANADA LIMITED CORPORATION (CA) | 2011-02-10 | — | — | WO | claimed |
| US-20080183388-A1 | Unobtrusive system and method for monitoring the physiological condition of a target user of a vehicle | 1A SMART START LLC | 2008-07-31 | — | — | US | claimed |
| WO-2008091621-A1 | AN UNOBITRUSIVE SYSTEM AND METHOD FOR MONITORING THE PHYSIOLOGICAL CONDITION OF A TARGET USER OF A VEHICLE | GOODRICH ALAN (US) | 2008-07-31 | — | — | WO | claimed |
| US-20050239164-A1 | Glutathione production | UNISEARCH LIMITED (AU) | 2005-10-27 | — | — | US | claimed |
| US-5205925-A | Recovering polychlorinated biphenyls from solution | TEXACO INC. (US) | 1993-04-27 | — | — | US | claimed |