Galactose

Galactose

SCHEMBL6900501

CCO.O=C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Galactose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
KDM4E B2RXH2 2/20 0.41
PDE4A P27815 1/20 0.41
USP2 O75604 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
AKR1B1 P15121 1/20 0.39
TOP1 P11387 1/20 0.34
MPI P34949 1/20 0.32
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL537703 1.00 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL329074 1.00 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL7958057 1.00 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL3872401 1.00 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL27994608 0.98 LMNA (0.48) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL9938071 0.98 LMNA (0.48) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL2341216 0.98 LMNA (0.48) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL28146511 0.95 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL1681820 0.94 LMNA (0.44) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL11509811 0.94 PDE4A (0.47) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106070943-A A kind of probiotic bacteria sugar-free soft sweet compositions and preparation method thereof 广州信天然医药科技有限公司 2016-11-09 CN claimed
EP-1044222-B1 OXIDATION IN SOLID STATE OF OXIDIZABLE GALACTOSE TYPE OF ALCOHOL CONFIGURATION CONTAINING POLYMER HERCULES INC (US) 2004-05-19 EP claimed
EP-1058735-B1 USE OF OXIDATION PROMOTING CHEMICALS IN THE OXIDATION OF OXIDIZABLE GALACTOSE TYPE OF ALCOHOL CONFIGURATION CONTAINING POLYMER HERCULES INC (US) 2003-07-30 EP claimed
US-6179962-B1 ADDING TO THE PULP WATER-SOLUBLE AND/OR WATER-DISPERSIBLE CATIONIC POLYMER AND OXIDIZED GUM HAVING A GALACTOSE TYPE OF ALCOHOL CONFIGURATION WHERE SOME ALCOHOLS ARE OXIDIZED TO ALDEHYDES; STRENGTH; PAPERMAKING; HERCULES INCORPORATED 2001-01-30 US claimed
US-6022717-A REACTING POLYMERS WITH GALACTOSE OXIDASE PRODUCING ALDEHYDE CONFIGURATIONS HERCULES INCORPORATED (US) 2000-02-08 US claimed
CN-118185589-A Sugar alcohol-biochar composite phase-change material and preparation method and application thereof 华南理工大学 2024-06-14 CN disclosed
CN-116334921-A Liquid softener compositions 狮王株式会社 2023-06-27 CN disclosed
CN-212516662-U Fireproof electric wire 东莞市盈晟电线有限公司 2021-02-09 CN disclosed
CN-212516662-U Fireproof electric wire 东莞市盈晟电线有限公司 2021-02-09 CN disclosed
CN-105734092-B A kind of method that enzyme process prepares D-Tag 江苏中酶生物科技有限公司 2019-07-16 CN disclosed
CN-107974474-A A kind of method of low cost production D-Tag 山东大学 2018-05-01 CN disclosed
CN-105734092-A Method for preparing D-tagatose by enzyme process 江苏中酶生物科技有限公司 2016-07-06 CN disclosed
US-6022717-A REACTING POLYMERS WITH GALACTOSE OXIDASE PRODUCING ALDEHYDE CONFIGURATIONS HERCULES INCORPORATED (US) 2000-02-08 US disclosed
WO-1999034009-A1 USE OF OXIDATION PROMOTING CHEMICALS IN THE OXIDATION OF OXIDIZABLE GALACTOSE TYPE OF ALCOHOL CONFIGURATION CONTAINING POLYMER HERCULES INCORPORATED (US) 1999-07-08 WO disclosed
WO-1999034058-A1 OXIDIZED GALACTOSE TYPE OF ALCOHOL CONFIGURATION CONTAINING POLYMER IN COMBINATION WITH CATIONIC POLYMERS FOR PAPER STRENGTH APPLICATIONS HERCULES INCORPORATED (US) 1999-07-08 WO disclosed
WO-1999033879-A1 OXIDATION IN SOLID STATE OF OXIDIZABLE GALACTOSE TYPE OF ALCOHOL CONFIGURATION CONTAINING POLYMER HERCULES INCORPORATED (US) 1999-07-08 WO disclosed
US-4916068-A IMMOBILIZED ENZYME; OXIDATION OF GALATONO-1,4-LACTONE KRAFT, INC. (US) 1990-04-10 US disclosed
US-4595659-A Using candida yeast microorganism KRAFT, INC. (US) 1986-06-17 US disclosed
EP-0146239-A2 Bioconversion production of ascorbic acid Kraft, Incorporated (US) 1985-06-26 EP disclosed
WO-1985001745-A1 BIOCONVERSION PRODUCTION OF ASCORBIC ACID KRAFT, INC. (US) 1985-04-25 WO disclosed