SCHEMBL329100

SCHEMBL329100

O=C([O-])CNCC(=O)[O-].[Ni+2]

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.50
CA1 P00915 4/20 0.42
CA12 O43570 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
FFAR3 O14843 2/20 0.40
HDAC3 O15379 2/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
CASP1 P29466 1/20 0.37
BBOX1 O75936 1/20 0.36
FABP3 P05413 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30917295 0.97 CA4 (0.53) CA4CA1CA12CA2CA9
SCHEMBL2947828 0.93 CA4 (0.50) CA4CA1CA12CA2CA9
Lithium Ion SCHEMBL3464173 0.93 CA4 (0.50) CA4CA1CA12CA2CA9
SCHEMBL284370 0.93 CA4 (0.56) CA4CA1CA12CA2CA9
SCHEMBL866376 0.93 CA4 (0.50) CA4CA1CA12CA2CA9
SCHEMBL5183804 0.93 CA4 (0.50) CA4CA1CA12CA2CA9
SCHEMBL10627868 0.93 CA4 (0.50) CA4CA1CA12CA2CA9
SCHEMBL1882178 0.93 CA4 (0.50) CA4CA1CA12CA2CA9
Zinc Ion SCHEMBL9393640 0.93 CA4 (0.50) CA4CA1CA12CA2CA9
Silver SCHEMBL17818673 0.93 CA4 (0.50) CA4CA1CA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040001-A Fe-Ni bimetallic carbon-based nano-enzyme and electrode capable of cooperating with electricity generation and wastewater treatment, and preparation method and application thereof 南京工业大学 2025-05-27 CN disclosed
CN-110785430-A RAGE proteins for the treatment of fibrosis and DNA damage mediated diseases 海德堡大学 2020-02-11 CN disclosed
EP-2382235-B1 NOVEL CAVIIDAE ALLERGEN AND USES THEREOF HILGER CHRISTIANE (LU) 2016-02-24 EP disclosed
US-20130198897-A1 MODIFYING ENZYME ACTIVITY IN PLANTS PHILIP MORRIS PRODUCTS S.A. (CH) 2013-08-01 US disclosed
US-20130116304-A1 TMEM195 ENCODES FOR TETRAHYDROBIOPTERIN-DEPENDENT ALKYLGLYCEROL MONOOXYGENASE ACTIVITY Werner, Ernst R. (AT) 2013-05-09 US disclosed
EP-2561068-A1 TMEM195 ENCODES FOR TETRAHYDROBIOPTERIN-DEPENDENT ALKYLGLYCEROL MONOOXYGENASE ACTIVITY Medizinische Universität Innsbruck (AT) 2013-02-27 EP disclosed
EP-2550358-A1 MODIFYING ENZYME ACTIVITY IN PLANTS Philip Morris Products S.A. (CH) 2013-01-30 EP disclosed
US-20120196325-A1 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CARBOHYDRATE UTILIZATION-RELATED PROTEINS AND USES THEREFOR NORTH CAROLINA STATE UNIVERSITY (US) 2012-08-02 US disclosed
US-20120149590-A1 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CELL SURFACE PROTEIN HOMOLOGUES AND USES THEREFORE NORTH CAROLINA STATE UNIVERSITY (US) 2012-06-14 US disclosed
US-8178337-B2 Lactobacillus acidophilus nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor NORTH CAROLINA STATE UNIVERSITY (US) 2012-05-15 US disclosed
WO-2005081959-A2 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFOR NORTH CAROLINA STATE UNIVERSITY (US) 2005-09-09 WO disclosed
US-20050123941-A1 Lactobacillus acidophilus nucleic acids encoding fructo-oligosaccharide utilization compounds and uses thereof NORTH CAROLINA STATE UNIVERSITY 2005-06-09 US disclosed
US-20050112612-A1 Lactobacillus acidophilus nucleic acid sequences encoding cell surface protein homologues and uses therefore NORTH CAROLINA STATE UNIVERSITY 2005-05-26 US disclosed
US-6869784-B2 Passivation of nerve agents by surface modified enzymes stabilized by non-covalent immobilization on robust, stable particles THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AMERICA (US) 2005-03-22 US disclosed
WO-2005001057-A2 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS ENCODING FRUCTO-OLIGOSACCHARIDE UTILIZATION COMPOUNDS AND USES THEREOF NORTH CAROLINA STATE UNIVERSITY (US) 2005-01-06 WO disclosed
WO-2004096992-A2 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CELL SURFACE PROTEIN HOMOLOGUES AND USES THEREFORE NORTH CAROLINA STATE UNIVERSITY (US) 2004-11-11 WO disclosed
US-20040029243-A1 Passivation of nerve agents by surface modified enzymes stabilized by non-covalent immobilization on robust, stable particles NAVY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2004-02-12 US disclosed
US-20030211586-A1 Passivation of nerve agents by surface modified enzymes stabilized by non-covalent immobilization on robust, stable particles THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2003-11-13 US disclosed
US-20020151030-A1 Claspin proteins and methods of use thereof CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-10-17 US disclosed
WO-2002033115-A2 CLASPIN PROTEINS AND METHODS OF USE THEREOF CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050123941-A1 Lactobacillus acidophilus nucleic acids encoding fructo-oligosaccharide utilization compounds and uses thereof FOS, FOSB, FBP1 CA4 176/4885CA1 158/4885CA12 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.