Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15586616 | 0.93 | KDM4A (0.49) | KDM4ANQO2CYP3A4ABCB1IDO1 | |
| SCHEMBL3293311 | 0.89 | CA14 (0.46) | KDM4ANQO2MAOAMAOBCYP3A4 | |
| SCHEMBL3244389 | 0.87 | MAOA (0.55) | MAOAMAOBCYP3A4TDP1CA1 | |
| SCHEMBL976700 | 0.87 | MAOA (0.55) | MAOAMAOBCYP3A4TDP1CA1 | |
| SCHEMBL28759617 | 0.81 | NQO2 (0.54) | KDM4ANQO2MAOAMAOBCYP3A4 | |
| SCHEMBL14208425 | 0.81 | SLC2A1 (0.54) | NQO2MEN1GAAKMT2A | |
| SCHEMBL23228318 | 0.80 | NQO2 (0.47) | KDM4ANQO2CYP3A4IDO1TDP1 | |
| SCHEMBL30442477 | 0.80 | MAOA (0.44) | MAOAMAOBCYP3A4TDP1CA1 | |
| SCHEMBL975698 | 0.80 | MAOA (0.44) | MAOAMAOBCYP3A4TDP1CA1 | |
| SCHEMBL6559442 | 0.79 | ATM (0.55) | MAOAMAOBCYP3A4IDO1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728041-B2 | Motuporamine mimic agents | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-20090069441-A1 | Motuporamine Mimic Agents | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2009-03-12 | — | — | US | disclosed |
| US-20070213397-A1 | Motuporamine mimic agents | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213397-A1 | Motuporamine mimic agents | MYADM, CD99, HNMT | KDM4A 2427/4885NQO2 3347/4885MAOA 742/4885 |
| US-20090069441-A1 | Motuporamine Mimic Agents | MYADM, CD99, HNMT | KDM4A 2427/4885NQO2 3347/4885MAOA 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.