SCHEMBL975698

SCHEMBL975698

CC(=O)c1ccc2c(CNCCCCCCNC(=O)OC(C)(C)C)c3ccccc3c(CNCCCCCCNC(=O)OC(C)(C)C)c2c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.44
▸ MAOB P27338 1/20 0.44
▸ CNR2 P34972 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.43
▸ PIM1 P11309 1/20 0.41
▸ PIM3 Q86V86 1/20 0.41
▸ SLC2A1 P11166 2/20 0.41
▸ TLR2 O60603 1/20 0.41
▸ TLR1 Q15399 1/20 0.41
▸ DRD2 P14416 2/20 0.40
▸ CA1 P00915 3/20 0.40
▸ CA2 P00918 3/20 0.40
▸ CA12 O43570 2/20 0.40
▸ CA9 Q16790 2/20 0.40
▸ MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30442477 1.00 MAOA (0.44) MAOAMAOBCNR2CYP3A4TDP1
SCHEMBL977328 0.91 BRD4 (0.44) MAOAMAOBCNR2CYP3A4TDP1
SCHEMBL976700 0.89 MAOA (0.55) MAOAMAOBCYP3A4TDP1PIM1
SCHEMBL3244389 0.89 MAOA (0.55) MAOAMAOBCYP3A4TDP1PIM1
SCHEMBL3291371 0.80 KDM4A (0.47) MAOAMAOBCNR2CYP3A4TDP1
SCHEMBL15134867 0.78 CA14 (0.47) MAOAMAOBCYP3A4TDP1PIM1
SCHEMBL16151782 0.75 MAOA (0.56) MAOAMAOBCYP3A4TDP1CA1
SCHEMBL15586616 0.75 KDM4A (0.49) CYP3A4DRD2
SCHEMBL13426175 0.74 ATM (0.55) MAOAMAOBCYP3A4TDP1CA1
SCHEMBL3293311 0.73 CA14 (0.46) MAOAMAOBCNR2CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822722-B2 Fluorescent hydrogel and method for producing the same, and sensor for measuring saccharides using the same TERUMO KABUSHIKI KAISHA (JP) 2014-09-02 — — US disclosed
US-8822722-B2 Fluorescent hydrogel and method for producing the same, and sensor for measuring saccharides using the same TERUMO KABUSHIKI KAISHA (JP) 2014-09-02 — — US disclosed
US-20130267800-A1 FLUORESCENT HYDROGEL AND METHOD FOR PRODUCING THE SAME, AND SENSOR FOR MEASURING SACCHARIDES USING THE SAME THE UNIVERSITY OF TOKYO (JP) 2013-10-10 — — US disclosed
US-20130267800-A1 FLUORESCENT HYDROGEL AND METHOD FOR PRODUCING THE SAME, AND SENSOR FOR MEASURING SACCHARIDES USING THE SAME THE UNIVERSITY OF TOKYO (JP) 2013-10-10 — — US disclosed
US-20130267800-A1 FLUORESCENT HYDROGEL AND METHOD FOR PRODUCING THE SAME, AND SENSOR FOR MEASURING SACCHARIDES USING THE SAME THE UNIVERSITY OF TOKYO (JP) 2013-10-10 — — US disclosed
US-7873398-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2011-01-18 — — US disclosed
US-7524985-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2009-04-28 — — US disclosed
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-12-25 — — US disclosed
US-7388110-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-06-17 — — US disclosed
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-01-24 — — US disclosed
EP-1619229-B1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO CORP (JP) 2007-04-11 — — EP disclosed
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA 2006-01-26 — — US disclosed
EP-1619229-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2006-01-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 MAOA 3610/4885MAOB 2739/4885CNR2 382/4885
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 MAOA 3313/4885MAOB 2355/4885CNR2 447/4885
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 MAOA 3313/4885MAOB 2355/4885CNR2 447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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