Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822257 | 0.88 | MAPT (0.44) | MAPTTSHRMGAMGAASI | |
| SCHEMBL481222 | 0.84 | TSHR (0.41) | MAPTTSHRFAAHMGAMGAA | |
| SCHEMBL8461302 | 0.83 | MAPT (0.45) | MAPTTSHRMGAMGAASI | |
| SCHEMBL11056232 | 0.83 | TSHR (0.41) | MAPTHSD17B10TSHRMGAMGAA | |
| SCHEMBL5284811 | 0.81 | MGAM (0.46) | MAPTTSHRFAAHMGAMGAA | |
| SCHEMBL6519648 | 0.80 | GAA (0.35) | TSHRFAAHMGAMGAASI | |
| SCHEMBL9773617 | 0.80 | MAPT (0.43) | MAPTTSHRMGAMGAASI | |
| SCHEMBL5282987 | 0.79 | ALDH1A1 (0.38) | TSHRFAAHMGAMGAASI | |
| SCHEMBL2809634 | 0.78 | CYP19A1 (0.37) | MAPTTSHRMGAMGAASI | |
| SCHEMBL10577206 | 0.78 | GAA (0.37) | HSD17B10TSHRFAAHMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2407493-B1 | SILICONE MONOMER | NOF CORP (JP) | 2014-04-23 | — | — | EP | disclosed |
| EP-2407493-A1 | SILICONE MONOMER | NOF Corporation (JP) | 2012-01-18 | — | — | EP | disclosed |