SCHEMBL3293135

SCHEMBL3293135

CC(C)(C)c1ccc2c(-c3ccc(-c4ccc(Br)cc4)cc3)c3ccccc3c(-c3ccc(-c4ccc(Br)cc4)cc3)c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 7/20 0.46
ALDH1A1 P00352 3/20 0.39
MAPK1 P28482 1/20 0.39
GPR84 Q9NQS5 1/20 0.35
NPC1 O15118 1/20 0.34
PLA2G1B P04054 1/20 0.34
NFKB1 P19838 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
PTGS2 P35354 1/20 0.34
PGR P06401 1/20 0.33
RORA P35398 1/20 0.33
RORC P51449 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511722 1.00 KIF11 (0.46) KIF11ALDH1A1MAPK1GPR84NPC1
SCHEMBL586251 0.98 KIF11 (0.47) KIF11ALDH1A1MAPK1GPR84NPC1
SCHEMBL29511820 0.98 KIF11 (0.47) KIF11ALDH1A1MAPK1GPR84NPC1
SCHEMBL29416708 0.88 KIF11 (0.46) KIF11ALDH1A1GPR84NPC1PLA2G1B
SCHEMBL261257 0.88 KIF11 (0.46) KIF11ALDH1A1GPR84NPC1PLA2G1B
SCHEMBL1322254 0.84 KIF11 (0.49) KIF11ALDH1A1GPR84NPC1PLA2G1B
SCHEMBL2700290 0.84 KIF11 (0.42) KIF11ALDH1A1MAPK1GPR84NPC1
SCHEMBL1063342 0.83 KIF11 (0.46) KIF11ALDH1A1GPR84NPC1PLA2G1B
SCHEMBL29886458 0.83 KIF11 (0.46) KIF11ALDH1A1GPR84NPC1PLA2G1B
SCHEMBL10030074 0.83 KIF11 (0.58) KIF11ALDH1A1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190355910-A1 Anthracene Derivative, Light Emitting Element Using the Same, and Light Emitting Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-11-21 US disclosed
US-10326078-B2 Anthracene derivative, light-emitting element using the same, and light-emitting device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-06-18 US disclosed
US-20170098776-A1 Anthracene Derivative, Light-Emitting Element Using the Same, and Light-Emitting Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-06 US disclosed
US-9478751-B2 Anthracene derivative, light emitting element using the same, and light emitting device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-10-25 US disclosed
US-9219235-B2 2015-12-22 US disclosed
US-20140364626-A1 Anthracene Derivative, Light Emitting Element Using the Same, and Light Emitting Device Using the Same SEMICONDUCTOR ENERGY LAB (JP) 2014-12-11 US disclosed
US-8815410-B2 Anthracene derivative, light emitting element using the same, and light emitting device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-26 US disclosed
US-7732064-B2 Anthracene derivative, and light-emitting element, light-emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-20080114178-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-15 US disclosed
US-20070267969-A1 Anthracene Derivative, Light Emitting Element Using the Same, and Light Emitting Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD., (JP) 2007-11-22 US disclosed
WO-2006070897-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPLIANCE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-07-06 WO disclosed
WO-2006070907-A1 ANTHRACENE DERIVATIVE, LIGHT EMITTING ELEMENT USING THE SAME, AND LIGHT EMITTING DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080114178-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Same AFF1, NOX1, RER1 KIF11 4523/4885ALDH1A1 44/4885MAPK1 1400/4885
US-20070267969-A1 Anthracene Derivative, Light Emitting Element Using the Same, and Light Emitting Device Using the Same NOX1, APEX1, CRY1 KIF11 4596/4885ALDH1A1 36/4885MAPK1 843/4885
US-20170098776-A1 Anthracene Derivative, Light-Emitting Element Using the Same, and Light-Emitting Device Using the Same NOX1, APEX1, CRY1 KIF11 4642/4885ALDH1A1 36/4885MAPK1 1136/4885
US-10326078-B2 Anthracene derivative, light-emitting element using the same, and light-emitting device using the same NOX1, APEX1, CRY1 KIF11 4642/4885ALDH1A1 36/4885MAPK1 1136/4885
US-20190355910-A1 Anthracene Derivative, Light Emitting Element Using the Same, and Light Emitting Device Using the Same NOX1, APEX1, CRY1 KIF11 4596/4885ALDH1A1 36/4885MAPK1 843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.