Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067388 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL152720 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL16226047 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL28194094 | 0.79 | ALDH1A1 (0.38) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL7745390 | 0.79 | GAA (0.39) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL28343695 | 0.79 | GABRA1 (0.43) | POLBRXRASMN1; SMN2TP53CYP3A4 | |
| SCHEMBL13707130 | 0.77 | ALDH1A1 (0.37) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL11307727 | 0.77 | CA1 (0.39) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL1052578 | 0.77 | KDM4E (0.41) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL1873446 | 0.77 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |