Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907993 | 0.83 | GAA (0.39) | ALDH1A1GAAKDM4ECYP3A4USP2 | |
| SCHEMBL152720 | 0.83 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL3293195 | 0.83 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL16226047 | 0.83 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL17453245 | 0.81 | MAPT (0.50) | ALDH1A1KDM4ECA1CA2KMT2A | |
| SCHEMBL7745390 | 0.80 | GAA (0.39) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL25564048 | 0.80 | TRPV1 (0.37) | PTGS1 | |
| SCHEMBL28194094 | 0.80 | ALDH1A1 (0.38) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL11307727 | 0.79 | CA1 (0.39) | ALDH1A1GAAKDM4ECA1CA2 | |
| SCHEMBL13707130 | 0.79 | ALDH1A1 (0.37) | ALDH1A1GAAKDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206809-A1 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY | VERA THERAPEUTICS INC (US) | 2021-07-08 | — | — | US | disclosed |
| US-20200354404-A1 | PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | US | disclosed |
| US-20190055190-A1 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO | NEUBASE THERAPEUTICS, INC. | 2019-02-21 | — | — | US | disclosed |
| US-20160367091-A9 | Personal Care Compositions Comprising a Di-Amido Gellant and Methods of Using | THE PROCTER & GAMBLE COMPANY | 2016-12-22 | — | — | US | disclosed |
| US-9334465-B2 | Structuring using an external structurant and a cosmotrope | THE PROCTER & GAMBLE COMPANY (US) | 2016-05-10 | — | — | US | disclosed |
| US-9334465-B2 | Structuring using an external structurant and a cosmotrope | THE PROCTER & GAMBLE COMPANY (US) | 2016-05-10 | — | — | US | disclosed |
| US-9091920-B2 | Photosensitive siloxane resin composition | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-20140179591-A1 | STRUCTURING USING AN EXTERNAL STRUCTURANT AND A COSMOTROPE | THE PROCTER & GAMBLE COMPANY (US) | 2014-06-26 | — | — | US | disclosed |
| US-20140179591-A1 | STRUCTURING USING AN EXTERNAL STRUCTURANT AND A COSMOTROPE | THE PROCTER & GAMBLE COMPANY (US) | 2014-06-26 | — | — | US | disclosed |
| EP-2746377-A1 | Improved structuring using an external structurant and a cosmotrope | The Procter & Gamble Company (US) | 2014-06-25 | — | — | EP | disclosed |
| EP-2570474-A1 | Stable water-soluble unit dose articles | The Procter and Gamble Company (US) | 2013-03-20 | — | — | EP | disclosed |
| US-20130065811-A1 | STABLE WATER-SOLUBLE UNIT DOSE ARTICLE | THE PROCTER & GAMBLE COMPANY | 2013-03-14 | — | — | US | disclosed |
| US-8309507-B2 | Processes for making fluid detergent compositions comprising a di-amido gellant | THE PROCTER & GAMBLE COMPANY (US) | 2012-11-13 | — | — | US | disclosed |
| US-8207107-B2 | Di-amido gellant for use in consumer product compositions | THE PROCTER & GAMBLE COMPANY (US) | 2012-06-26 | — | — | US | disclosed |
| US-20120151881-A1 | PROCESSES FOR MAKING FLUID DETERGENT COMPOSITIONS COMPRISING A DI-AMIDO GELLANT | FERNANDEZ PRIETO SUSANA (ES) | 2012-06-21 | — | — | US | disclosed |
| US-8168579-B2 | Fluid detergent compositions comprising a di-amido gellant, and processes for making | THE PROCTER AND GAMBLE COMPANY (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110224455-A1 | Di-Amido Gellant For Use In Consumer Product Compositions | THE PROCTER & GAMBLE COMPANY | 2011-09-15 | — | — | US | disclosed |
| US-20110224455-A1 | Di-Amido Gellant For Use In Consumer Product Compositions | THE PROCTER & GAMBLE COMPANY | 2011-09-15 | — | — | US | disclosed |
| US-20110220536-A1 | Fluid Detergent Compositions Comprising a Di-Amido Gellant, and Processes for Making | THE PROCTER & GAMBLE COMPANY | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190055190-A1 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO | TARBP1, TIA1, SSB | ALDH1A1 4569/4885GAA 1406/4885KDM4E 3859/4885 |
| US-20110224455-A1 | Di-Amido Gellant For Use In Consumer Product Compositions | DAGLA, GNPAT, CDIPT | ALDH1A1 1506/4885GAA 661/4885KDM4E 4312/4885 |
| US-20200354404-A1 | PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF | DNPEP, PEPD, ANPEP | ALDH1A1 4718/4885GAA 685/4885KDM4E 4843/4885 |
| US-20210206809-A1 | PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY | AGO2, TARBP1, TPR | ALDH1A1 4394/4885GAA 1285/4885KDM4E 3560/4885 |
| US-20130065811-A1 | STABLE WATER-SOLUBLE UNIT DOSE ARTICLE | IDUA, AQP1, DLST | ALDH1A1 3400/4885GAA 3108/4885KDM4E 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.