SCHEMBL3293266

SCHEMBL3293266

[CH2]c1cc(F)ccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1310830 0.79
SCHEMBL14413 0.75
SCHEMBL2840953 0.75
SCHEMBL29350499 0.75
SCHEMBL30411804 0.75
SCHEMBL1044966 0.72
Methane SCHEMBL8873095 0.72 ALDH1A1 (0.48)
SCHEMBL755034 0.72
SCHEMBL2913077 0.72 ALDH1A1 (0.48)
SCHEMBL4768705 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3692101-B1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTR S R L (IT) 2022-01-12 EP claimed
EP-3692101-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES Alfa Instruments S.r.l. (IT) 2020-08-12 EP claimed
WO-2019068935-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTRUMENTS S.R.L. (IT) 2019-04-11 WO claimed
EP-2680851-B1 FUSED BICYCLIC HETEROCYCLES USEFUL AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS MERCK SHARP & DOHME (US) 2016-08-17 EP claimed
US-8907086-B2 Fused bicyclic heterocycles useful as dipeptidyl peptidase-IV inhibitors MERCK SHARP & DOHME CORP. (US) 2014-12-09 US claimed
EP-2680851-A2 FUSED BICYCLIC HETEROCYCLES USEFUL AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS Merck Sharp & Dohme Corp. (US) 2014-01-08 EP claimed
US-20130324562-A1 FUSED BICYCLIC HETEROCYCLES USEFUL AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS MERCK SHARP & DOHME LLC 2013-12-05 US claimed
WO-2012118945-A2 FUSED BICYCLIC HETEROCYCLES USEFUL AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS MERCK SHARP & DOHME CORP. (US) 2012-09-07 WO claimed
WO-2024133360-A1 NOVEL CANNABINOID-INSPIRED INHIBITORS OF AUTOTAXIN EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2024-06-27 WO disclosed
EP-4380936-A1 PYRAZOLOPYRIDINONE COMPOUNDS BeiGene, Ltd. (KY) 2024-06-12 EP disclosed
CN-118084891-A 1,3, 4-Oxadiazole derivative containing 1,2, 4-triazole and preparation method and application thereof 贵阳学院 2024-05-28 CN disclosed
CN-117836296-A Pyrazolopyridone compounds 百济神州有限公司 2024-04-05 CN disclosed
CN-111925360-B 1-heterocyclylisochromanyl compounds and analogs for the treatment of CNS disorders 赛诺维信制药公司 2024-03-22 CN disclosed
CN-116568675-A Cyclic isothiourea derivatives as CXCR4 modulators 埃尔米乌治疗公司 2023-08-08 CN disclosed
US-20060105970-A1 Avermectins substituted in the 4\"-position having pesticidal properties SYNGENTA CROP PROTECTION, INC. 2006-05-18 US disclosed
CN-1671391-A Novel methods and compositions for pain relief ALLERGAN INC (US) 2005-09-21 CN disclosed
CN-1549819-A 4 '-deoxy-4' - (S) -amino avermectin derivatives �����ɷ� 2004-11-24 CN disclosed
CN-1494549-A 4' -substituted avermectins with pesticidal properties �����ɷ� 2004-05-05 CN disclosed
EP-1389216-A2 AVERMECTINS SUBSTITUTED IN THE 4\"-POSITION HAVING PESTICIDAL PROPERTIES Syngenta Participations AG (CH) 2004-02-18 EP disclosed
WO-2002068441-A2 AVERMECTINS SUBSTITUTED IN THE 4'-POSITION HAVING PESTICIDAL PROPERTIES SYNGENTA PARTICIPATIONS AG (CH) 2002-09-06 WO disclosed