Methane

Methane

SCHEMBL8873095

C.Fc1ccc(Br)c(F)c1

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
KDM1A O60341 2/20 0.43
KCNH2 Q12809 2/20 0.43
KDM1B Q8NB78 1/20 0.43
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NFE2L2 Q16236 3/20 0.39
IDO1 P14902 2/20 0.38
AGXT P21549 2/20 0.38
KIF11 P52732 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350499 0.97
SCHEMBL14413 0.97
SCHEMBL2913077 0.94 ALDH1A1 (0.48) ALDH1A1KDM1AKCNH2KDM1BCES2
Formaldehyde SCHEMBL27870893 0.89 CES2 (0.44) ALDH1A1KDM1AKCNH2KDM1BCES2
SCHEMBL28058902 0.85 NFE2L2 (0.47) ALDH1A1KDM1AKCNH2KDM1BCES2
SCHEMBL1349378 0.83 EPAS1 (0.41) ALDH1A1KDM1AKCNH2KDM1BCES2
Formic Acid SCHEMBL27678088 0.83 CES2 (0.45) ALDH1A1KDM1AKCNH2KDM1BCES2
SCHEMBL257619 0.79 KIF11 (0.49) ALDH1A1KDM1AKCNH2KDM1BIDO1
SCHEMBL30411804 0.79
SCHEMBL2840953 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5629332-A FUNGICIDES NIHON NOHYAKU CO., LTD. (JP) 1997-05-13 US disclosed