SCHEMBL2840953

SCHEMBL2840953

Fc1ccc(Br)c(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30411804 1.00
SCHEMBL14413 0.81
SCHEMBL29350499 0.81
SCHEMBL2913077 0.79 ALDH1A1 (0.48)
Methane SCHEMBL8873095 0.79 ALDH1A1 (0.48)
SCHEMBL29462675 0.79 PKM (0.39)
SCHEMBL15213955 0.79 PKM (0.39)
SCHEMBL6203814 0.79
SCHEMBL441585 0.79
SCHEMBL6731816 0.77 CA3 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1126833-A4 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES INC (US) 2004-09-08 EP claimed
EP-1150565-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION bioscience AG (DE) 2001-11-07 EP claimed
EP-1126833-A2 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2001-08-29 EP claimed
WO-2000045635-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2000-08-10 WO claimed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 WO claimed
EP-0466698-A1 PREPARATION OF 2-HALOFLUOROBENZENE MALLINCKRODT, INC. (US) 1992-01-22 EP claimed
WO-1990011987-A1 PREPARATION OF 2-HALOFLUOROBENZENE MALLINCKRODT, INC. (US) 1990-10-18 WO claimed
US-4918251-A Preparation of 2-halofluorobenzene MALLINCKRODT, INC. (US) 1990-04-17 US claimed
EP-4347610-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT PALLADIUM (II) COMPLEXES FOR OLED APPLICATIONS Versitech Limited (CN) 2024-04-10 EP disclosed
CN-112430234-B Novel KRAS G12C protein inhibitor and preparation method and application thereof 信达生物制药(苏州)有限公司 2023-04-28 CN disclosed
WO-2022253221-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT PALLADIUM (II) COMPLEXES FOR OLED APPLICATIONS VERSITECH LIMITED (CN) 2022-12-08 WO disclosed
US-11299457-B2 Chemical compounds GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) 2022-04-12 US disclosed
CN-112430234-A Novel KRAS G12C protein inhibitor and preparation method and application thereof 信达生物制药(苏州)有限公司 2021-03-02 CN disclosed
US-20200270210-A1 CHEMICAL COMPOUNDS GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED 2020-08-27 US disclosed
EP-0238272-B1 INTERMEDIATES USEFUL IN THE PRODUCTION OF PESTICIDES BTG INTERNATIONAL LIMITED (GB) 1992-05-13 EP disclosed
EP-0466698-A1 PREPARATION OF 2-HALOFLUOROBENZENE MALLINCKRODT, INC. (US) 1992-01-22 EP disclosed
US-5068403-A INTERMEDIATES USEFUL IN THE PRODUCTION OF PESTICIDES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1991-11-26 US disclosed
WO-1990011987-A1 PREPARATION OF 2-HALOFLUOROBENZENE MALLINCKRODT, INC. (US) 1990-10-18 WO disclosed
US-4918251-A Preparation of 2-halofluorobenzene MALLINCKRODT, INC. (US) 1990-04-17 US disclosed
EP-0238272-A2 Intermediates useful in the production of pesticides BTG INTERNATIONAL LIMITED (GB) 1987-09-23 EP disclosed