SCHEMBL3293517

SCHEMBL3293517

[NaH].c1ccc(Sc2nnn[nH]2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
HPGD P15428 2/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MGLL Q99685 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NOTUM Q6P988 1/20 0.32
HTT P42858 2/20 0.32
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452473 0.98 ALDH1A1 (0.35) ALDH1A1HPGDMAPTSMN1; SMN2MGLL
SCHEMBL6552282 0.96 ALDH1A1 (0.34) ALDH1A1HPGDMAPTSMN1; SMN2MGLL
SCHEMBL6234901 0.78 NR1H2 (0.48) ALDH1A1HPGDMAPTSMN1; SMN2HSD17B10
SCHEMBL7585509 0.77 TSHR (0.40) ALDH1A1HPGDSMN1; SMN2HTTLMNA
SCHEMBL21552590 0.77 NOTUM (0.41) ALDH1A1HPGDMAPTSMN1; SMN2NOTUM
SCHEMBL9852530 0.76 GAA (0.33) ALDH1A1HPGDMAPTSMN1; SMN2HTT
SCHEMBL10972518 0.73 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL5199349 0.72 PNP (0.36) ALDH1A1HPGDMAPTSMN1; SMN2HSD17B10
SCHEMBL6546417 0.72 ALDH1A1 (0.47) ALDH1A1MAPTSMN1; SMN2LMNACYP1A2
SCHEMBL9594853 0.71 TSHR (0.39) ALDH1A1SMN1; SMN2HSD17B10MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0576052-A1 Method of forming a photographic coupler capable of forming a wash-out dye EASTMAN KODAK COMPANY (US) 1993-12-29 EP claimed
US-5264582-A Reaction of hydroxyaryl aldehyde or ketone with a halomethyl compound to form ether compound and reducing the product then halogenation and reaction with photographic coupler EASTMAN KODAK COMPANY (US) 1993-11-23 US claimed
US-5239081-A Preparation of photographic compounds EASTMAN KODAK COMPANY (US) 1993-08-24 US claimed
US-7732124-B2 Silver halide color photographic light-sensitive material and color image-forming method FUJIFILM CORPORATION (JP) 2010-06-08 US disclosed
US-7611829-B2 Silver halide color photographic light-sensitive material and color image-forming method FUJIFILM CORPORATION (JP) 2009-11-03 US disclosed
US-20090130613-A1 Silver Halide color photographic light-sensitive material and color image-forming method DEGUCHI YASUAKI 2009-05-21 US disclosed
EP-1914594-A2 Silver halide color photographic light-sensitive material and color image-forming method FUJIFILM Corporation (JP) 2008-04-23 EP disclosed
US-20070154853-A1 Silver halide color photographic light-sensitive material and color image-forming method FUJI PHOTO FILM CO., LTD. (JP) 2007-07-05 US disclosed
EP-1709483-A4 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND COLOR IMAGE-FORMING METHOD FUJIFILM CORP (JP) 2007-06-27 EP disclosed
US-7150962-B2 Method for forming images and silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2006-12-19 US disclosed
US-7135258-B2 Imaging member adhered to vacuous core base EASTMAN KODAK COMPANY (US) 2006-11-14 US disclosed
EP-0720048-A2 Photographic element containing pyrazolone pug releasing coupler and imaging process employing same EASTMAN KODAK COMPANY (US) 1996-07-03 EP disclosed
EP-0540118-B1 Photographic material and process EASTMAN KODAK CO (US) 1994-12-14 EP disclosed
US-5362880-A Method of preparing a magenta development inhibitor releasing coupler EASTMAN KODAK COMPANY (US) 1994-11-08 US disclosed
EP-0577210-A1 A method of preparing a magenta development inhibitor releasing coupler EASTMAN KODAK COMPANY (US) 1994-01-05 EP disclosed
EP-0576052-A1 Method of forming a photographic coupler capable of forming a wash-out dye EASTMAN KODAK COMPANY (US) 1993-12-29 EP disclosed
US-5264582-A Reaction of hydroxyaryl aldehyde or ketone with a halomethyl compound to form ether compound and reducing the product then halogenation and reaction with photographic coupler EASTMAN KODAK COMPANY (US) 1993-11-23 US disclosed
EP-0540118-A1 Photographic material and process EASTMAN KODAK COMPANY (US) 1993-05-05 EP disclosed
US-4605753-A Silver sulfinate physical developer for heat-developable photographic films E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-08-12 US disclosed
US-4529689-A Silver sulfinate photothermographic films E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-07-16 US disclosed