Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679444 | 0.80 | HSD17B1 (0.36) | SMN1; SMN2ACHEALDH1A1 | |
| SCHEMBL452473 | 0.78 | ALDH1A1 (0.35) | NOTUMSMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL6552282 | 0.77 | ALDH1A1 (0.34) | NOTUMSMN1; SMN2HPGDMAPTHTT | |
| SCHEMBL3293517 | 0.77 | ALDH1A1 (0.34) | NOTUMSMN1; SMN2HPGDMAPTHTT | |
| SCHEMBL9594853 | 0.74 | TSHR (0.39) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL575896 | 0.73 | ACHE (0.58) | NOTUMHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL29543680 | 0.73 | ACHE (0.58) | NOTUMHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL29468631 | 0.73 | ACHE (0.58) | NOTUMHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL10710202 | 0.69 | ACHE (0.52) | NOTUMHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL3894284 | 0.68 | ACHE (0.50) | HTR1AHTR3ASMN1; SMN2IDO1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380629-A1 | METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTOACTIVATED AGENTS | VIBRANT HOLDINGS, LLC | 2021-12-09 | — | — | US | disclosed |
| EP-3790985-A1 | METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTACTIVATED AGENTS | Vibrant Holdings, LLC (US) | 2021-03-17 | — | — | EP | disclosed |
| WO-2019217704-A9 | METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTACTIVATED AGENTS | VIBRANT HOLDINGS, LLC (US) | 2020-12-10 | — | — | WO | disclosed |
| WO-2019217704-A1 | METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTACTIVATED AGENTS | VIBRANT HOLDINGS, LLC (US) | 2019-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380629-A1 | METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTOACTIVATED AGENTS | POLN, PCNA, POLM | NOTUM 4127/4885HTR1A 4108/4885HTR3A 3825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.