Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452473 | 0.78 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDLMNAL3MBTL1 | |
| SCHEMBL3293517 | 0.77 | ALDH1A1 (0.34) | ALDH1A1HPGDLMNAHTTSMN1; SMN2 | |
| SCHEMBL15220060 | 0.73 | TSHR (0.67) | TSHRTP53PKMALDH1A1RXRA | |
| SCHEMBL71112 | 0.73 | TSHR (0.67) | TSHRTP53PKMALDH1A1RXRA | |
| SCHEMBL15220063 | 0.73 | TSHR (0.67) | TSHRTP53PKMALDH1A1RXRA | |
| Hydrochloric Acid SCHEMBL7138094 | 0.71 | TSHR (0.63) | TSHRTP53PKMALDH1A1RXRA | |
| SCHEMBL9459884 | 0.71 | TSHR (0.63) | TSHRTP53PKMALDH1A1RXRA | |
| Barium SCHEMBL9452526 | 0.71 | TSHR (0.63) | TSHRTP53PKMALDH1A1RXRA | |
| SCHEMBL2819906 | 0.70 | KDM4E (0.50) | TSHRTP53ALDH1A1KDM4ESRD5A2 | |
| SCHEMBL28489775 | 0.69 | KDM4E (0.49) | TSHRTP53ALDH1A1KDM4ESRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045282-B1 | Radiographic UV/Blue-sensitive film material and intensifying screen-film combination | AGFA GEVAERT (BE) | 2002-10-16 | — | — | EP | disclosed |
| US-6403276-B1 | SILVER BROMIDE EMULSION COMPRISING SPECTRAL SENSITIZER AND AZACYANINE DYE | AGFA-GEVAERT (BE) | 2002-06-11 | — | — | US | disclosed |
| US-6316176-B1 | SILVER HALIDE EMULSION, BINDER AND SENSITIZER OF SULFUR AND ORGANOTELLURIUM COMPOUNDS | AGFA-GEVAERT (BE) | 2001-11-13 | — | — | US | disclosed |
| EP-1070986-A1 | Photosensitive silver halide element comprising chemically sensitized emulsion grains and method to prepare them | AGFA-GEVAERT naamloze vennootschap (BE) | 2001-01-24 | — | — | EP | disclosed |
| EP-1045282-A1 | Radiographic UV/Blue-sensitive film material and intensifying screen-film combination | AGFA-GEVAERT N.V. (BE) | 2000-10-18 | — | — | EP | disclosed |
| EP-0590715-B1 | Emulsion preparation using simultaneous chemical and spectral sensitization in the presence of a salt | AGFA GEVAERT NV (BE) | 1999-03-17 | — | — | EP | disclosed |
| EP-0449340-B1 | Photographic stabilizers containing a developer group | AGFA GEVAERT NV (BE) | 1996-10-16 | — | — | EP | disclosed |
| EP-0590715-A1 | Emulsion preparation using simultaneous chemical and spectral sensitization in the presence of a salt | AGFA-GEVAERT N.V. (BE) | 1994-04-06 | — | — | EP | disclosed |
| US-5156940-A | Used in photographic silver halide emulsions and materials | AGFA-GEVAERT, N.V. (BE) | 1992-10-20 | — | — | US | disclosed |
| EP-0449340-A1 | Photographic stabilizers containing a developer group | AGFA-GEVAERT N.V. (BE) | 1991-10-02 | — | — | EP | disclosed |