Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29849782 | 0.97 | PTGS2 (0.43) | PTGS2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL13295272 | 0.86 | ALDH1A1 (0.33) | PTGS2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL15975759 | 0.86 | ALDH1A1 (0.47) | PTGS2ALDH1A1HSD17B10BCL2L1MAPK1 | |
| SCHEMBL2005519 | 0.86 | ALDH1A1 (0.47) | PTGS2ALDH1A1HSD17B10BCL2L1MAPK1 | |
| SCHEMBL3292244 | 0.86 | ALDH1A1 (0.47) | PTGS2ALDH1A1HSD17B10BCL2L1MAPK1 | |
| SCHEMBL21766542 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HSD17B10HPGDDCUN1D1 | |
| SCHEMBL30713831 | 0.84 | MAPK1 (0.64) | ALDH1A1HSD17B10HPGDMAPK1DCUN1D1 | |
| SCHEMBL20955829 | 0.84 | IDO1 (0.36) | PTGS2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL20226006 | 0.84 | ALDH1A1 (0.36) | PTGS2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL9319701 | 0.83 | ALDH1A1 (0.53) | PTGS2ALDH1A1HSD17B10BCL2L1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728138-B2 | Bis-triphenylsilyl compounds and their application on organic electronic device | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-06-01 | — | — | US | disclosed |
| US-7728138-B2 | Bis-triphenylsilyl compounds and their application on organic electronic device | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-06-01 | — | — | US | disclosed |
| US-20090131670-A1 | charge transfer; light emitters; electroluminesence, phosphorescence | Cheng, Chien-Hong (TW) | 2009-05-21 | — | — | US | disclosed |
| US-20090131670-A1 | charge transfer; light emitters; electroluminesence, phosphorescence | Cheng, Chien-Hong (TW) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131670-A1 | charge transfer; light emitters; electroluminesence, phosphorescence | CCNT1, CCNE2, CCNT2 | PTGS2 1842/4885ALDH1A1 2933/4885HSD17B10 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.