SCHEMBL20955829

SCHEMBL20955829

Sc1ccccc1-c1ccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 1/20 0.36
▸ ALDH1A1 P00352 4/20 0.32
▸ HSD17B10 Q99714 2/20 0.32
▸ HPGD P15428 1/20 0.32
▸ BCL2L1 Q07817 1/20 0.32
▸ CYP2A6 P11509 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ KIF11 P52732 1/20 0.31
▸ NPSR1 Q6W5P4 2/20 0.31
▸ MAPT P10636 2/20 0.31
▸ CASP3 P42574 1/20 0.31
▸ SENP8 Q96LD8 1/20 0.31
▸ SENP7 Q9BQF6 1/20 0.31
▸ SENP6 Q9GZR1 1/20 0.31
▸ PTGS2 P35354 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ APAF1 O14727 1/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3293807 0.84 PTGS2 (0.40) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL29849782 0.82 PTGS2 (0.43) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL12609346 0.80 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL164357 0.79 ALDH1A1 (0.48) IDO1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL20955830 0.79 PTAFR (0.38) IDO1PTGS2ENPP1
SCHEMBL3893272 0.77 ALDH1A1 (0.46) IDO1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL27326199 0.77 ALDH1A1 (0.46) IDO1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL102647 0.77 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Biphenyl SCHEMBL3199503 0.77 ALDH1A1 (0.50) IDO1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL27455692 0.77 ALDH1A1 (0.46) IDO1ALDH1A1HSD17B10HPGDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480205-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF SAN APRO LTD (JP) 2022-04-13 — — EP disclosed
CN-108884110-B Sulfonium salt, photoacid generator, photocurable composition, and cured product thereof 三亚普罗股份有限公司 2021-09-14 — — CN disclosed
US-10683266-B2 Sulfonium salt, photoacid generator, photocurable composition, and cured product thereof SAN APRO LTD. (JP) 2020-06-16 — — US disclosed
US-20190300476-A1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF SAN-APRO LTD. (JP) 2019-10-03 — — US disclosed
EP-3480205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF San-Apro Ltd. (JP) 2019-05-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190300476-A1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTOCURABLE COMPOSITION, AND CURED PRODUCT THEREOF ASIC1, TST, SPIN2B IDO1 4429/4885ALDH1A1 821/4885HSD17B10 3162/4885
US-10683266-B2 Sulfonium salt, photoacid generator, photocurable composition, and cured product thereof ASIC1, TST, SPIN2B IDO1 4429/4885ALDH1A1 821/4885HSD17B10 3162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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