Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3850312 | 0.82 | CA1 (0.42) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL1139376 | 0.82 | PDK1 (0.51) | PDK1PDK2PDK3PDK4POLB | |
| SCHEMBL618106 | 0.82 | PDK1 (0.70) | PDK1PDK2PDK3PDK4CA1 | |
| SCHEMBL27430704 | 0.82 | TSHR (0.55) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL7880575 | 0.81 | PDK1 (0.68) | PDK1PDK2PDK3PDK4CA1 | |
| SCHEMBL2709623 | 0.80 | PDK1 (0.44) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL9824176 | 0.79 | TSHR (0.47) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL15998606 | 0.79 | PDK1 (0.43) | PDK1PDK2PDK3PDK4CXCR1 | |
| SCHEMBL27677695 | 0.77 | KCNMA1 (0.53) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL7299817 | 0.77 | GAA (0.56) | PDK1PDK2PDK3PDK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741352-B2 | KCNQ channel modulating compounds and their pharmaceutical use | NEUROSEARCH A/S (DK) | 2010-06-22 | — | — | US | disclosed |
| EP-1620093-B1 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1620093-B1 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1620093-A4 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-10-31 | — | — | EP | disclosed |
| US-7208450-B2 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | BAYER CROPSCIENCE AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-20060173058-A1 | Kcnq channel modulating compounds and their pharmaceutical use | NEUROSEARCH A/S (DK) | 2006-08-03 | — | — | US | disclosed |
| WO-2006081165-A1 | IMPROVED PROCESS FOR PREPARING (DIHALOPROPENYL)PHENYLAKEYL SUBSTITUTED BENZOXAZOLES | BAYER CROPSCIENCE AG (DE) | 2006-08-03 | — | — | WO | disclosed |
| EP-1620093-A2 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2006-02-01 | — | — | EP | disclosed |
| US-20050171356-A1 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | FMC CORPORATION | 2005-08-04 | — | — | US | disclosed |
| WO-2004099105-A2 | PESTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171356-A1 | Pesticidal (dihalopropenyl) phenylalkyl substituted benzoxazole and benzothiazole derivatives | DDT, PDHX, CYP4X1 | PDK1 1784/4885PDK2 2062/4885PDK3 1468/4885 |
| US-20060173058-A1 | Kcnq channel modulating compounds and their pharmaceutical use | KCNQ1, KCNQ2, KCNQ5 | PDK1 1118/4885PDK2 1086/4885PDK3 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.