SCHEMBL3295284

SCHEMBL3295284

CCCCCCCC[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@@H]1NC(C)=O

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.65
▸ ALDH1A1 P00352 2/20 0.51
▸ THRB P10828 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ PYGB P11216 2/20 0.43
▸ LGALS8 O00214 1/20 0.42
▸ LGALS3 P17931 1/20 0.42
▸ LGALS4 P56470 1/20 0.42
▸ CD69 Q07108 2/20 0.41
▸ GAA P10253 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21947408 1.00 MAPK1 (0.65) MAPK1ALDH1A1THRBSMN1; SMN2PYGB
SCHEMBL6942761 1.00 MAPK1 (0.65) MAPK1ALDH1A1THRBSMN1; SMN2PYGB
SCHEMBL3296000 1.00 MAPK1 (0.65) MAPK1ALDH1A1THRBSMN1; SMN2PYGB
SCHEMBL6944012 1.00 MAPK1 (0.65) MAPK1ALDH1A1THRBSMN1; SMN2PYGB
SCHEMBL3295994 1.00 MAPK1 (0.65) MAPK1ALDH1A1THRBSMN1; SMN2PYGB
SCHEMBL23478019 1.00 MAPK1 (0.65) MAPK1ALDH1A1THRBSMN1; SMN2PYGB
SCHEMBL3295282 1.00 MAPK1 (0.65) MAPK1ALDH1A1THRBSMN1; SMN2PYGB
SCHEMBL23848966 0.94 MAPK1 (0.61) MAPK1ALDH1A1THRBSMN1; SMN2PYGB
SCHEMBL21415430 0.89 MAPK1 (0.51) MAPK1ALDH1A1THRBSMN1; SMN2PYGB
SCHEMBL23735602 0.88 MAPK1 (0.56) MAPK1ALDH1A1THRBSMN1; SMN2PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7049300-B2 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans L'OREAL (FR) 2006-05-23 — — US claimed
US-20040048785-A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans SOCIETE L'OREAL S.A. (FR) 2004-03-11 — — US claimed
EP-1345919-A2 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF L'OREAL (FR) 2003-09-24 — — EP claimed
WO-2002051803-A2 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF L'OREAL (FR) 2002-07-04 — — WO claimed
WO-2002051828-A2 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF L'OREAL (FR) 2002-07-04 — — WO claimed
EP-1345919-B1 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF OREAL (FR) 2013-05-22 — — EP disclosed
US-7732414-B2 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans L'OREAL S.A. (FR) 2010-06-08 — — US disclosed
US-20060223763-A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans L'OREAL S.A. (FR) 2006-10-05 — — US disclosed
US-7049300-B2 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans L'OREAL (FR) 2006-05-23 — — US disclosed
US-20040048785-A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans SOCIETE L'OREAL S.A. (FR) 2004-03-11 — — US disclosed
EP-1345919-A2 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF L'OREAL (FR) 2003-09-24 — — EP disclosed
WO-2002051803-A2 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF L'OREAL (FR) 2002-07-04 — — WO disclosed
WO-2002051828-A2 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF L'OREAL (FR) 2002-07-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223763-A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans CSGALNACT1, FUT6, AREG MAPK1 2007/4885ALDH1A1 2637/4885THRB 2233/4885
US-20040048785-A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans CSGALNACT1, FUT6, AREG MAPK1 2007/4885ALDH1A1 2637/4885THRB 2233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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