SCHEMBL329583

SCHEMBL329583

CC[Si](CC)(CC)CCCN1CCCN(C)C1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8406001 0.78 HRH3 (0.52) HRH3
SCHEMBL8405981 0.78 HRH3 (0.52) HRH3
SCHEMBL8405887 0.78 HRH3 (0.52) HRH3
SCHEMBL8404181 0.78 HRH3 (0.52) HRH3
SCHEMBL497703 0.77 KDM4E (0.31)
SCHEMBL329441 0.76 HRH3 (0.30) HRH3
SCHEMBL22380707 0.76 GNAI3 (0.44) HRH3
SCHEMBL13363935 0.73 DRD2 (0.35)
SCHEMBL30221866 0.72 KEAP1 (0.43) HRH3
SCHEMBL19792080 0.72 HRH3 (0.41) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2407507-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE JSR CORP (JP) 2016-09-28 EP disclosed
EP-2407507-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE JSR Corporation (JP) 2012-01-18 EP disclosed
US-20110319519-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE JSR CORPORATION (JP) 2011-12-29 US disclosed