Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297546 | 0.88 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBHTTNPSR1 | |
| SCHEMBL3301492 | 0.86 | KDM4E (0.40) | ALDH1A1SMN1; SMN2NPSR1KDM4EMAPT | |
| SCHEMBL3298741 | 0.81 | CA1 (0.39) | ALDH1A1SMN1; SMN2HTTNPSR1HSD17B10 | |
| SCHEMBL2942871 | 0.78 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2POLBHTTNPSR1 | |
| SCHEMBL3296081 | 0.77 | MAPT (0.44) | ALDH1A1SMN1; SMN2POLBNPSR1HSD17B10 | |
| SCHEMBL2009215 | 0.77 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2POLBHTTNPSR1 | |
| SCHEMBL3296971 | 0.77 | KDM4E (0.47) | ALDH1A1SMN1; SMN2HSD17B10KDM4EMAPT | |
| SCHEMBL3296571 | 0.76 | CALM1 (0.37) | ALDH1A1SMN1; SMN2POLBHTTHSD17B10 | |
| SCHEMBL22276350 | 0.75 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2POLBHTTNPSR1 | |
| SCHEMBL22820476 | 0.75 | KDM4E (0.47) | ALDH1A1SMN1; SMN2POLBHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741393-B2 | Organic silicon-based compound and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-22 | — | — | US | disclosed |
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | ARSA, OR10J3, HDAC10 | ALDH1A1 1865/4885SMN1; SMN2 1035/4885POLB 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.