Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293003 | 0.93 | IDO1 (0.36) | IDO1KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL3288612 | 0.84 | DDB1 (0.43) | BCHECNR2DDB1CRBNIDO1 | |
| SCHEMBL3289243 | 0.83 | LMNA (0.40) | IDO1KDM4EALDH1A1HPGDRAB9A | |
| Trifluoroacetic Acid SCHEMBL3288201 | 0.80 | KDM4E (0.37) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3293923 | 0.79 | P2RY14 (0.39) | CNR2DDB1CRBNKDM4EALDH1A1 | |
| SCHEMBL3983498 | 0.79 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3983514 | 0.79 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3812384 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3291726 | 0.78 | CA12 (0.44) | BCHECNR2KDM4EALDH1A1HPGD | |
| SCHEMBL4396358 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718621-B2 | Macrolones—amino substituted quinolones | GLAXO GROUP LTD. (GB) | 2010-05-18 | — | — | US | disclosed |
| US-20080090773-A1 | Macrolones - Amino Substituted Quinolones | GLAXO GROUP LIMITED (GB) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090773-A1 | Macrolones - Amino Substituted Quinolones | MRPL21, Q6ZSR9, QARS1 | BCHE 2344/4885CNR2 4675/4885DDB1 2059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.