SCHEMBL3296533

SCHEMBL3296533

CCCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.50
PTGES O14684 3/20 0.50
ALOX5 P09917 3/20 0.50
HMGCR P04035 2/20 0.48
MAPK1 P28482 3/20 0.46
CA2 P00918 1/20 0.46
GAA P10253 5/20 0.45
KMT2A Q03164 3/20 0.45
ATM Q13315 3/20 0.43
NPSR1 Q6W5P4 3/20 0.43
XBP1 P17861 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 3/20 0.42
TSHR P16473 3/20 0.42
MEN1 O00255 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
BLM P54132 2/20 0.42
HIF1A Q16665 2/20 0.42
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL220369 0.96 HMGCR (0.47) PPARGPTGESALOX5HMGCRMAPK1
SCHEMBL284122 0.94 HMGCR (0.46) PPARGPTGESALOX5HMGCRMAPK1
SCHEMBL21616894 0.94 HMGCR (0.46) PPARGPTGESALOX5HMGCRMAPK1
SCHEMBL18855 0.94 HMGCR (0.46) PPARGPTGESALOX5HMGCRMAPK1
SCHEMBL8954906 0.94 HMGCR (0.46) PPARGPTGESALOX5HMGCRMAPK1
SCHEMBL11459320 0.94 HMGCR (0.46) PPARGPTGESALOX5HMGCRMAPK1
SCHEMBL5415838 0.94 HMGCR (0.46) PPARGPTGESALOX5HMGCRMAPK1
SCHEMBL17491249 0.94 HMGCR (0.46) PPARGPTGESALOX5HMGCRMAPK1
SCHEMBL208069 0.94 HMGCR (0.46) PPARGPTGESALOX5HMGCRMAPK1
SCHEMBL17491241 0.94 HMGCR (0.46) PPARGPTGESALOX5HMGCRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1713891-B1 LUBRICANT COMPOSITIONS COMPRISING AN ANTIOXIDANT BLEND CHEMTURA CORP (US) 2013-07-10 EP claimed
US-7494960-B2 Lubricant compositions comprising an antioxidant blend CROMPTON CORPORATION (US) 2009-02-24 US claimed
EP-1713891-A1 LUBRICANT COMPOSITIONS COMPRISING AN ANTIOXIDANT BLEND CHEMTURA CORPORATION (US) 2006-10-25 EP claimed
WO-2005078054-A1 LUBRICANT COMPOSITIONS COMPRISING AN ANTIOXIDANT BLEND CHEMTURA CORPORATION (US) 2005-08-25 WO claimed
US-20050170978-A1 Lubricant compositions comprising an antioxidant blend CHEMTURA CORPORATION 2005-08-04 US claimed
EP-4263481-B1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC (US) 2025-06-18 EP disclosed
US-12173247-B2 Reaction product of an organic amine and glycidol and its use as a friction modifier HUNTSMAN PETROCHEMICAL LLC 2024-12-24 US disclosed
US-20240018440-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC 2024-01-18 US disclosed
EP-4263481-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER Huntsman Petrochemical LLC (US) 2023-10-25 EP disclosed
US-11512262-B2 Azaphenothiazines and azaphenoxazines as antioxidants UNIVERSITY OF OTTAWA (CA) 2022-11-29 US disclosed
WO-2022132364-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC (US) 2022-06-23 WO disclosed
EP-3562921-B1 LUBRICATING COMPOSITION INCLUDING N-ALKYLATED DIANILINE LUBRIZOL CORP (US) 2022-04-27 EP disclosed
WO-2006005711-A1 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2006-01-19 WO disclosed
WO-2006005713-A1 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2006-01-19 WO disclosed
US-20060009366-A1 Lubricating oil composition SHELL OIL COMPANY 2006-01-12 US disclosed
EP-1594943-A2 LUBRICATING OIL COMPOSITIONS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2005-11-16 EP disclosed
WO-2005078054-A1 LUBRICANT COMPOSITIONS COMPRISING AN ANTIOXIDANT BLEND CHEMTURA CORPORATION (US) 2005-08-25 WO disclosed
US-20050170978-A1 Lubricant compositions comprising an antioxidant blend CHEMTURA CORPORATION 2005-08-04 US disclosed
US-20040224860-A1 Lubricating oil compositions SHELL OIL COMPANY 2004-11-11 US disclosed
WO-2004074412-A2 LUBRICATING OIL COMPOSITIONS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2004-09-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11512262-B2 Azaphenothiazines and azaphenoxazines as antioxidants GPX4, LPO, GPX1 PPARG 251/4885PTGES 557/4885ALOX5 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.