Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531145 | 0.95 | CYP19A1 (1.00) | CYP19A1 | |
| Rogletimide SCHEMBL9372682 | 0.85 | CYP19A1 (1.00) | CYP19A1 | |
| Rogletimide SCHEMBL4281 | 0.85 | CYP19A1 (1.00) | CYP19A1 | |
| Rogletimide SCHEMBL28110686 | 0.83 | CYP19A1 (0.94) | CYP19A1 | |
| SCHEMBL10514138 | 0.76 | CYP19A1 (0.68) | CYP19A1 | |
| Safingol SCHEMBL28069970 | 0.76 | CYP19A1 (0.62) | CYP19A1 | |
| Safingol SCHEMBL28140538 | 0.75 | CYP19A1 (0.61) | CYP19A1 | |
| SCHEMBL13465305 | 0.74 | CYP19A1 (0.60) | CYP19A1 | |
| SCHEMBL20805215 | 0.71 | CYP19A1 (0.60) | CYP19A1 | |
| Phenglutarimide SCHEMBL1649930 | 0.70 | CYP19A1 (0.56) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140080794-A1 | Methods and Compositions for the Treatment of Estrogen-Dependent Hyperproliferative Uterine Disorders | VIVUS INC (US) | 2014-03-20 | — | — | US | disclosed |
| US-20100087402-A1 | Methods and compositions for the treatment of estrogen-dependent hyperproliferative uterine disorders | VIVUS, INC. (US) | 2010-04-08 | — | — | US | disclosed |