Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.59 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.57 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.57 |
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6978866 | 0.98 | ITGB3 (0.58) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL3290955 | 0.84 | ITGB3 (0.81) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL13094271 | 0.83 | ITGB3 (0.66) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL13094273 | 0.83 | ITGB3 (0.66) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL6983890 | 0.83 | ITGB3 (0.78) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL10441109 | 0.82 | CYP1A2 (0.54) | — | |
| Hydrochloric Acid SCHEMBL30701848 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL3093114 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL8502841 | 0.82 | ITGB3 (0.68) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL30314839 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2BF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732412-B2 | Methods of treatment using novel LHRH antagonists having improved solubility properties | ZENTARIS GMBH (DE) | 2010-06-08 | — | — | US | disclosed |
| US-20060281685-A1 | METHODS OF TREATMENT USING NOVEL LHRH ANTAGONISTS HAVING IMPROVED SOLUBILITY PROPERTIES | ZENTARIS GMBH (DE) | 2006-12-14 | — | — | US | disclosed |
| US-7148195-B2 | LHRH antagonists having improved solubility properties | ZENTARIS GMBH (DE) | 2006-12-12 | — | — | US | disclosed |
| US-20040266695-A1 | Novel LHRH antagonists having improved solubility properties | BERND MICHAEL | 2004-12-30 | — | — | US | disclosed |
| US-6627609-B1 | Peptides which contain N-methylated amino acid units and have improved water solubility. Medicaments in which the peptides according to the invention are contained can be used for the treatment of hormone- dependent tumours and | ZENTARIS AG (DE) | 2003-09-30 | — | — | US | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281685-A1 | METHODS OF TREATMENT USING NOVEL LHRH ANTAGONISTS HAVING IMPROVED SOLUBILITY PROPERTIES | GNRHR, PRLHR, FSHR | ITGB3 4090/4885ITGA2B 4610/4885F2 898/4885 |
| US-20040266695-A1 | Novel LHRH antagonists having improved solubility properties | LHCGR, GNRHR, PRLHR | ITGB3 4858/4885ITGA2B 4879/4885F2 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.