SCHEMBL3297828

SCHEMBL3297828

CCc1ccc([SiH](O[SiH](c2ccc(CC)c(OC)c2)c2ccc(CC)c(OC)c2)c2ccc(CC)c(OC)c2)cc1OC

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.42
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
APLNR P35414 1/20 0.37
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PTGS2 P35354 1/20 0.34
CYP3A4 P08684 1/20 0.34
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3296118 0.85 TAAR1 (0.42) TAAR1KDM4EL3MBTL1
SCHEMBL3296512 0.84 L3MBTL1 (0.43) MAPTTSHRMAPK1KDM4EL3MBTL1
SCHEMBL3299978 0.80 GRIN2D (0.31)
SCHEMBL3300325 0.80 MAPT (0.39) MAPTTSHRL3MBTL1
SCHEMBL3294269 0.78 CA2 (0.48) TSHRMAPK1KDM4ECYP3A4CA2
SCHEMBL8296534 0.75 MAOB (0.57) TAAR1MAPTCYP3A4
SCHEMBL3296969 0.75 NQO2 (0.36) TAAR1MAPTKDM4ECYP3A4
SCHEMBL3301588 0.73 MAPT (0.43) GAAMAPTTSHRMAPK1HTT
SCHEMBL10187102 0.72 L3MBTL1 (0.60) TAAR1GAAMAPTTSHRMAPK1
SCHEMBL31172821 0.72 APLNR (0.66) TAAR1MAPTAPLNRCYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741393-B2 Organic silicon-based compound and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same ARSA, OR10J3, HDAC10 TAAR1 866/4885GAA 530/4885MAPT 2685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.