SCHEMBL3298262

SCHEMBL3298262

FC(F)c1cccc(C(F)F)n1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 2/20 0.50
PGK2 P07205 2/20 0.50
IDH1 O75874 2/20 0.39
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
TGFBR1 P36897 8/20 0.33
ADORA2A P29274 1/20 0.32
TGFBR2 P37173 1/20 0.30
IRAK4 Q9NWZ3 1/20 0.30
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21649830 0.87 PGK1 (0.42) PGK1PGK2IDH1ALDH1A1POLB
SCHEMBL5177258 0.84 PGK1 (0.39) PGK1PGK2IDH1ALDH1A1POLB
SCHEMBL29337106 0.83 IRAK4 (0.43) PGK1PGK2IDH1IRAK4
SCHEMBL17923104 0.82 NOS2 (0.44) PGK1PGK2IDH1ALDH1A1POLB
SCHEMBL29413191 0.82 S1PR2 (0.38) PGK1PGK2IDH1ALDH1A1POLB
SCHEMBL104442 0.82 S1PR2 (0.38) PGK1PGK2IDH1ALDH1A1POLB
SCHEMBL5179094 0.82 PGK1 (0.47) PGK1PGK2IDH1ALDH1A1POLB
SCHEMBL2019306 0.82 CCR1 (0.48) PGK1PGK2ALDH1A1ADORA2A
SCHEMBL31616873 0.82 L3MBTL1 (0.46) PGK1PGK2IDH1ALDH1A1TGFBR1
SCHEMBL17667865 0.82 L3MBTL1 (0.46) PGK1PGK2IDH1ALDH1A1TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732540-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-20090018012-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed