SCHEMBL3298485

SCHEMBL3298485

O=[N+]([O-])C1([N+](=O)O)CNC1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
NLRP3 Q96P20 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL9249321 0.87 CA5A (0.42) CA5ACA5BNLRP3
SCHEMBL3298482 0.84 NLRP3 (0.32) NLRP3
Hydrochloric Acid SCHEMBL3746492 0.81 NLRP3 (0.31) NLRP3
Nitric Acid SCHEMBL11044841 0.72
SCHEMBL7249119 0.70
SCHEMBL272478 0.62 NLRP3 (0.36) CA5ACA5BNLRP3
SCHEMBL14911002 0.62
Nitric Acid SCHEMBL6680089 0.62
Nitric Acid SCHEMBL11794277 0.60 CA5A (0.57) CA5ACA5B
Piperazine SCHEMBL5875381 0.60 CA5A (0.57) CA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008054538-A2 LEAD-FREE PRIMARY EXPLOSIVES LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-05-08 WO claimed
US-20080091029-A1 Lead-free primary explosives LOS ALAMOS NATIONAL SECURITY, LLC 2008-04-17 US claimed
US-5395945-A Salt formation, neutralization THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1995-03-07 US claimed
US-7741353-B2 Lead-free primary explosives LOS ALAMOS NATIONAL SECURITY, LLC (US) 2010-06-22 US disclosed
WO-2008054538-A2 LEAD-FREE PRIMARY EXPLOSIVES LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-05-08 WO disclosed
US-20080091029-A1 Lead-free primary explosives LOS ALAMOS NATIONAL SECURITY, LLC 2008-04-17 US disclosed