Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294124 | 1.00 | ELANE (0.39) | ELANEHPGDALDH1A1KDM4ECES2 | |
| SCHEMBL3297934 | 1.00 | ELANE (0.39) | ELANEHPGDALDH1A1KDM4ECES2 | |
| SCHEMBL1086753 | 0.85 | CES2 (0.34) | ELANEHPGDALDH1A1KDM4ECES2 | |
| SCHEMBL1088007 | 0.85 | CES2 (0.34) | ELANEHPGDALDH1A1KDM4ECES2 | |
| SCHEMBL1087730 | 0.85 | CES2 (0.34) | ELANEHPGDALDH1A1KDM4ECES2 | |
| SCHEMBL1943281 | 0.85 | ELANE (0.46) | ELANEHPGDALDH1A1KDM4ECES2 | |
| SCHEMBL2184872 | 0.81 | ELANE (0.46) | ELANEHPGDALDH1A1KDM4ECES2 | |
| SCHEMBL17123279 | 0.81 | ELANE (0.41) | ELANEHPGDALDH1A1KDM4ECES2 | |
| SCHEMBL31029265 | 0.77 | ESR1 (0.30) | — | |
| SCHEMBL30525946 | 0.77 | ESR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7736634-B2 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2010-06-15 | — | — | US | claimed |
| US-20070196326-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2007-08-23 | — | — | US | claimed |
| US-20060252953-A1 | Process for the production of silyl carboxylate monomers | SIGMA COATINGS B.V. (NL) | 2006-11-09 | — | — | US | claimed |
| EP-1431301-A1 | Process for the production of silyl carboxylate monomers | SIGMA COATINGS B.V. (NL) | 2004-06-23 | — | — | EP | claimed |
| US-7736634-B2 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2010-06-15 | — | — | US | disclosed |
| EP-1795551-B1 | Polyorganosilylated carboxylate monomers and polymers and process for the preparation thereof | SIGMAKALON SERVICES B V (NL) | 2009-12-30 | — | — | EP | disclosed |
| US-7595370-B2 | Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems | PPG B.V. (NL) | 2009-09-29 | — | — | US | disclosed |
| US-20070196326-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2007-08-23 | — | — | US | disclosed |
| EP-1795551-A1 | Polyorganosilylated carboxylate monomers and polymers and process for the preparation thereof | Sigmakalon Services B.V. (NL) | 2007-06-13 | — | — | EP | disclosed |
| US-20060252953-A1 | Process for the production of silyl carboxylate monomers | SIGMA COATINGS B.V. (NL) | 2006-11-09 | — | — | US | disclosed |
| US-20060142516-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2006-06-29 | — | — | US | disclosed |
| US-20040236048-A1 | Binders with low content in hydrolysable monomer suitable for self-polishing antifouling paints | SIGMA COATINGS B.V. (NL) | 2004-11-25 | — | — | US | disclosed |
| EP-1431301-A1 | Process for the production of silyl carboxylate monomers | SIGMA COATINGS B.V. (NL) | 2004-06-23 | — | — | EP | disclosed |
| EP-1380611-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SigmaKalon Group B.V. (NL) | 2004-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252953-A1 | Process for the production of silyl carboxylate monomers | ACSL1, SUCLA2, MSMO1 | ELANE 2684/4885HPGD 417/4885ALDH1A1 47/4885 |
| US-20070196326-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | PRMT9, MRPL9, CD59 | ELANE 4665/4885HPGD 3761/4885ALDH1A1 1429/4885 |
| US-20060142516-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | C1R, C9, PCBP1 | ELANE 3970/4885HPGD 3178/4885ALDH1A1 2342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.