SCHEMBL3299382

SCHEMBL3299382

O=C1c2ccccc2C(=O)c2cc(OS(=O)(=O)O)ccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.48
MCL1 Q07820 1/20 0.48
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
TTR P02766 1/20 0.46
NPC1 O15118 4/20 0.46
ALDH1A1 P00352 4/20 0.46
RAB9A P51151 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
MAPK1 P28482 3/20 0.46
ELANE P08246 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
CDC25B P30305 1/20 0.44
ADORA2A P29274 1/20 0.43
MAPT P10636 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5935687 0.94 GAA (0.50) BCL2MCL1GLAGAATTR
SCHEMBL10708659 0.80 PKLR (0.47) BCL2MCL1TTRNPC1ALDH1A1
SCHEMBL6795080 0.80 CA2 (0.58) BCL2MCL1NPC1ALDH1A1RAB9A
SCHEMBL11023360 0.80 ADORA2A (0.47) MCL1GLAGAANPC1ALDH1A1
Water SCHEMBL15848113 0.79 PKLR (0.46) BCL2MCL1NPC1ALDH1A1RAB9A
SCHEMBL10489419 0.78 MEN1 (0.55) BCL2MCL1TTRNPC1ALDH1A1
SCHEMBL28185341 0.76 TTR (0.52) BCL2MCL1TTRNPC1ALDH1A1
SCHEMBL14124745 0.75 MAPT (0.49) BCL2MCL1GAANPC1ALDH1A1
SCHEMBL29669681 0.75 CA1 (0.66) GLAGAASMN1; SMN2MAPK1TDP1
SCHEMBL1593352 0.75 CA1 (0.66) GLAGAASMN1; SMN2MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7740656-B2 Implantable heart valve prosthetic devices having intrinsically conductive polymers MEDTRONIC, INC. (US) 2010-06-22 US disclosed
US-7629400-B2 Image making medium HYMAN SYDNEY 2009-12-08 US disclosed
CN-100474110-C Selected acid generators and their use in radiation-sensitive element imaging processes EASTMAN KODAK CO (US) 2009-04-01 CN disclosed
EP-1691855-A2 IMPLANTABLE HEART VALVE PROSTHETIC DEVICES HAVING INTRINSICALLY CONDUCTIVE POLYMERS Medtronic, Inc. (US) 2006-08-23 EP disclosed
CN-1656426-A Selected acid generators and their use in radiation-sensitive element imaging processes KODAK POLYCHROME GRAPHICS LLC (US) 2005-08-17 CN disclosed
WO-2005049103-A2 IMPLANTABLE HEART VALVE PROSTHETIC DEVICES HAVING INTRINSICALLY CONDUCTIVE POLYMERS MEDTRONIC, INC. (US) 2005-06-02 WO disclosed
US-20050107872-A1 Implantable heart valve prosthetic devices having intrinsically conductive polymers MEDTRONIC,INC. 2005-05-19 US disclosed
EP-1508072-A2 ACID GENERATING AGENTS AND THEIR USE IN PROCESSES FOR IMAGING RADIATION-SENSITIVE ELEMENTS Kodak Polychrome Graphics LLC (US) 2005-02-23 EP disclosed
US-6787281-B2 SUCH AS 2-METHOXY-4-(PHENYLAMINO)-BENZENEDIAZONIUM DODECYL SULFATE (MSDS), WHICH DOES NOT CONTAIN OZONE DEPLETION ELEMENTS (FLUORINE, HEAVY METALS); POLLUTION CONTROL; LITHOGRAPHY KODAK POLYCHROME GRAPHICS LLC 2004-09-07 US disclosed
WO-2004036314-A2 ACID GENERATING AGENTS AND THEIR USE IN PROCESSES FOR IMAGING RADIATION-SENSITIVE ELEMENTS KODAK POLYCHROME GRAPHICS LLC (US) 2004-04-29 WO disclosed
US-20030219673-A1 Selected acid generating agents and their use in processes for imaging radiation-sensitive elements FPC INC. 2003-11-27 US disclosed
US-20030035917-A1 Image making medium HYMAN SYDNEY (US) 2003-02-20 US disclosed
US-6218134-B1 INTRODUCING LABELED SPECIFIC BINDING SUBSTANCE AND LIQUID TEST SAMPLE INTO MATRIX OF DEVICE, BINDING SUBSTANCE SPECIFICALLY COMPETES WITH ANALYTE FOR OTHER SPECIFIC BINDING SUBSTANCE, SIGNAL IS GENERATED WHICH CHANGES DISTRIBUTION MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2001-04-17 US disclosed
EP-0143406-B1 LIQUID REACTIVE DYE COMPOSITIONS AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-03-14 EP disclosed