Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.58 |
| ▸ | CA9 | Q16790 | 7/20 | 0.58 |
| ▸ | CA1 | P00915 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299382 | 0.80 | BCL2 (0.48) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL12998250 | 0.79 | STS (0.51) | CA2CA9CA1STS | |
| SCHEMBL10708659 | 0.79 | PKLR (0.47) | CA2NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| Water SCHEMBL15848113 | 0.77 | PKLR (0.46) | CA2NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10489419 | 0.77 | MEN1 (0.55) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6797983 | 0.76 | STS (0.56) | CA2CA9CA1NPC1ALDH1A1 | |
| SCHEMBL4645032 | 0.76 | PTPN1 (0.58) | CA2CA9CA1NPC1ALDH1A1 | |
| SCHEMBL10613734 | 0.74 | MAOA (0.61) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL28482981 | 0.74 | MEN1 (0.53) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL9750123 | 0.73 | CA2 (1.00) | CA2CA9CA1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |