Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | F12 | P00748 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10083761 | 0.90 | ADORA1 (0.54) | ADORA1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL821475 | 0.89 | L3MBTL1 (0.56) | ADORA1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL3945635 | 0.89 | ADORA1 (0.60) | ADORA1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL3299661 | 0.86 | ADORA1 (0.70) | ADORA1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL821465 | 0.85 | KMT2A (0.49) | ADORA1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL6576666 | 0.85 | ADORA1 (0.49) | ADORA1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL28580981 | 0.84 | MPO (0.50) | ADORA1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL11166514 | 0.84 | ADORA1 (0.63) | ADORA1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL20072315 | 0.82 | ADORA1 (0.43) | ADORA1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL11591466 | 0.82 | HDAC1 (0.60) | LMNASMN1; SMN2KMT2AMEN1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541966-A2 | Process for preparing amide derivatives from halomines and acid halides | AMERICAN CYANAMID COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |