Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16933910 | 0.85 | ACHE (0.48) | MPOTAAR1RIPK1ADORA2AADORA1 | |
| SCHEMBL3306943 | 0.84 | HTR2A (0.50) | MPOTAAR1LMNAGAA | |
| SCHEMBL7052559 | 0.83 | TAAR1 (0.48) | MPOTAAR1CES2CES1BCHE | |
| SCHEMBL21662616 | 0.83 | MPO (0.42) | MPOGPR84FFAR1TAAR1RIPK1 | |
| SCHEMBL17552658 | 0.81 | TAAR1 (0.41) | MPOGPR84FFAR1TAAR1CES2 | |
| SCHEMBL283845 | 0.81 | TAAR1 (0.41) | MPOGPR84FFAR1TAAR1CES2 | |
| SCHEMBL214409 | 0.81 | TAAR1 (0.52) | MPOTAAR1CES2CES1BCHE | |
| SCHEMBL12815296 | 0.80 | MPO (0.40) | MPOGPR84FFAR1TAAR1RIPK1 | |
| SCHEMBL10476233 | 0.80 | MAOB (0.50) | MPOTAAR1IDO1 | |
| Hydrochloric Acid SCHEMBL11299004 | 0.79 | IDO1 (0.40) | MPOTAAR1CES2CES1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | claimed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | claimed |
| CN-109411805-B | Electrolyte and lithium secondary battery including the same | 三星电子株式会社 | 2023-07-11 | — | — | CN | disclosed |
| US-20170338504-A1 | POLYMER AND POLYMER ELECTROLYTE MEMBRANE COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-11-23 | — | — | US | disclosed |
| US-20170327607-A1 | POLYMER AND POLYMER ELECTROLYTE MEMBRANE COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-11-16 | — | — | US | disclosed |
| US-20170331136-A1 | POLYMER ELECTROLYTE MEMBRANE | LG CHEM, LTD. (KR) | 2017-11-16 | — | — | US | disclosed |
| US-20170317370-A1 | POLYMER AND POLYMER ELECTROLYTE MEMBRANE COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-11-02 | — | — | US | disclosed |
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | disclosed |
| US-8299072-B2 | Pyrazolylmethylamine compounds as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-10-30 | — | — | US | disclosed |
| US-20100094006-A1 | NOVEL PYRAZOLYLMETHYLAMINE COMPOUNDS AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-04-15 | — | — | US | disclosed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1B, CACNA1C, ORAI1 | MPO 4413/4885GPR84 2440/4885FFAR1 1462/4885 |
| US-20100094006-A1 | NOVEL PYRAZOLYLMETHYLAMINE COMPOUNDS AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1I, CACNA1C, ORAI1 | MPO 4639/4885GPR84 920/4885FFAR1 2156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.