Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061956 | 0.87 | TAAR1 (0.67) | TAAR1IDO1AOC3MPOHTR2A | |
| SCHEMBL2210035 | 0.87 | TAAR1 (0.67) | TAAR1IDO1AOC3MPOHTR2A | |
| SCHEMBL17748504 | 0.87 | TAAR1 (0.48) | TAAR1CES2BCHECES1CXCR2 | |
| SCHEMBL2339012 | 0.85 | TAAR1 (0.41) | TAAR1CES2BCHECES1CXCR2 | |
| SCHEMBL21312964 | 0.85 | TAAR1 (0.41) | TAAR1CES2BCHECES1CXCR2 | |
| Hydrochloric Acid SCHEMBL2211422 | 0.85 | TAAR1 (0.64) | TAAR1IDO1MPOHTR2ASLC6A4 | |
| SCHEMBL5610129 | 0.85 | TAAR1 (0.41) | TAAR1CES2BCHECES1CXCR2 | |
| SCHEMBL4476574 | 0.85 | RIPK1 (0.42) | TAAR1CES2BCHECES1CXCR2 | |
| SCHEMBL5584389 | 0.85 | TAAR1 (0.41) | TAAR1CES2BCHECES1CXCR2 | |
| SCHEMBL5608928 | 0.85 | TAAR1 (0.41) | TAAR1CES2BCHECES1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759558-B2 | REDUCTION OF HALOGEN-SUBSTITUTED TEREPHTHALIC ACIDS AND REACTION WITH AN ALKYLATING AGENT, SULFURIC ACID, ALKYL- OR ARYLSULFONIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-06 | — | — | US | disclosed |
| US-20020156330-A1 | Process for preparing halogen-substituted dibenzyl alcohols, these halogen-substituted dibenzyl alcohols and their use | LANXESS DEUTSCHLAND GMBH (DE) | 2002-10-24 | — | — | US | disclosed |
| US-4071570-A | ANTIARRHYTHMIC AGENTS | MERCK & CO., INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-3978127-A | ANTIARRHYTHMIC | MERCK & CO., INC. (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156330-A1 | Process for preparing halogen-substituted dibenzyl alcohols, these halogen-substituted dibenzyl alcohols and their use | ADH1A, ADH1C, ADH5 | TAAR1 640/4885CES2 158/4885BCHE 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.