SCHEMBL330078

SCHEMBL330078

Fc1cccc2c1CNC2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 2/20 0.42
IKBKB O14920 2/20 0.41
DRD2 P14416 1/20 0.40
DRD3 P35462 1/20 0.40
PNMT P11086 2/20 0.38
MAOB P27338 1/20 0.37
RAF1 P04049 1/20 0.36
RPS6KB1 P23443 1/20 0.36
MAPK1 P28482 1/20 0.36
AKT1 P31749 1/20 0.36
AKT2 P31751 1/20 0.36
KDR P35968 1/20 0.36
PRKAG1 P54619 1/20 0.36
MAP2K1 Q02750 1/20 0.36
PRKAA1 Q13131 1/20 0.36
MAPK14 Q16539 1/20 0.36
DYRK2 Q92630 1/20 0.36
NEK1 Q96PY6 1/20 0.36
PRKAB1 Q9Y478 1/20 0.36
HTR2C P28335 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29972587 1.00 CD44 (0.42) CD44IKBKBDRD2DRD3PNMT
Hydrochloric Acid SCHEMBL621622 0.98 CD44 (0.41) CD44IKBKBDRD2DRD3PNMT
Hydrochloric Acid SCHEMBL30453968 0.98 CD44 (0.41) CD44IKBKBDRD2DRD3PNMT
SCHEMBL620774 0.86 IKBKB (0.44) CD44IKBKBDRD2DRD3RAF1
SCHEMBL29587158 0.81 CD44 (0.61) CD44DRD2DRD3PNMTMAOB
SCHEMBL327075 0.81 CD44 (0.61) CD44DRD2DRD3PNMTMAOB
SCHEMBL3052029 0.81 PNMT (0.61) CD44PNMTMAOBHTR2CADRA2A
Hydrochloric Acid SCHEMBL29586475 0.79 CD44 (0.59) CD44DRD2DRD3PNMTMAOB
Hydrochloric Acid SCHEMBL1124513 0.79 CD44 (0.59) CD44DRD2DRD3PNMTMAOB
Hydrochloric Acid SCHEMBL2258194 0.79 PNMT (0.59) CD44PNMTMAOBHTR2CADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7939668-B2 Ruthenium complexes as catalysts for metathesis reactions ROCHE PALO ALTO LLC (US) 2011-05-10 US claimed
US-20090275714-A1 New Ruthenium Complexes as Catalysts for Metathesis Reactions ROCHE PALO ALTO LLC 2009-11-05 US claimed
US-4777181-A ANTIDIABETIC AGENTS BEIERSDORF AG (DE) 1988-10-11 US claimed
EP-0228640-A1 Substituted 4-fluoro-isoindolines, method for their preparation and their use as well as compositions containing them Beiersdorf Aktiengesellschaft (DE) 1987-07-15 EP claimed
EP-4707279-A1 SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUND AS PHARMACEUTICAL FOR TREATMENT OR PREVENTION OF COVID-19 Albius Sciences Beta Pte. Ltd. (SG) 2026-03-11 EP disclosed
US-20240174631-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY RECOVERY THERAPEUTICS, INC. 2024-05-30 US disclosed
CN-117157069-A Compounds, compositions and methods for modulating FGF activity 康复治疗公司 2023-12-01 CN disclosed
US-20230365567-A1 COMPOUNDS Esfam Biotech Pty Ltd (AU) 2023-11-16 US disclosed
CN-116987021-A Novel isoindoline derivative with anti-tumor effect as well as preparation method and application thereof 北京中医药大学 2023-11-03 CN disclosed
CN-116829558-A Compounds of formula (I) 艾斯法姆生物技术股份有限公司 2023-09-29 CN disclosed
EP-4238962-A1 METHOD FOR PRODUCING DIIMINOPYRROLE COMPOUND Godo Shigen Co., Ltd. (JP) 2023-09-06 EP disclosed
WO-2023116779-A1 DIALKYNE COMPOUND AND USE THEREOF 上海艾力斯医药科技股份有限公司 2023-06-29 WO disclosed
US-5026856-A Bactericides WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1991-06-25 US disclosed
EP-0343560-A2 Isoindoline derivative WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1989-11-29 EP disclosed
US-4777181-A ANTIDIABETIC AGENTS BEIERSDORF AG (DE) 1988-10-11 US disclosed
US-4777181-A ANTIDIABETIC AGENTS BEIERSDORF AG (DE) 1988-10-11 US disclosed
US-4777181-A ANTIDIABETIC AGENTS BEIERSDORF AG (DE) 1988-10-11 US disclosed
EP-0228640-A1 Substituted 4-fluoro-isoindolines, method for their preparation and their use as well as compositions containing them Beiersdorf Aktiengesellschaft (DE) 1987-07-15 EP disclosed
EP-0228640-A1 Substituted 4-fluoro-isoindolines, method for their preparation and their use as well as compositions containing them Beiersdorf Aktiengesellschaft (DE) 1987-07-15 EP disclosed
EP-0228640-A1 Substituted 4-fluoro-isoindolines, method for their preparation and their use as well as compositions containing them Beiersdorf Aktiengesellschaft (DE) 1987-07-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365567-A1 COMPOUNDS CD81, CD47, CD59 CD44 152/4885IKBKB 2216/4885DRD2 1402/4885
US-20240174631-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY FGF1, FGF2, FGFR1 CD44 3337/4885IKBKB 3761/4885DRD2 4709/4885
US-20090275714-A1 New Ruthenium Complexes as Catalysts for Metathesis Reactions HABP2, CYP3A7, ACE CD44 4611/4885IKBKB 2179/4885DRD2 4414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.