Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 1.00 |
| ▸ | RAB9A | P51151 | 14/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.86 |
| ▸ | TP53 | P04637 | 5/20 | 0.86 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.68 |
| ▸ | RELA | Q04206 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970418 | 1.00 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL6799157 | 0.93 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL8769709 | 0.88 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL8770881 | 0.88 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL6361263 | 0.88 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL30341896 | 0.88 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL22192206 | 0.88 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL22495349 | 0.87 | RAB9A (0.81) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL11911277 | 0.87 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL12228183 | 0.87 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119998260-A | Process for preparing amides from esters | 巴斯夫欧洲公司 | 2025-05-13 | — | — | CN | disclosed |
| WO-2024050825-A1 | COMPOUNDS AS MLKL INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2024-03-14 | — | — | WO | disclosed |
| US-10442779-B2 | Compositions and methods for treating Friedreich's ataxia | FRATAGENE THERAPEUTICS S.R.L. (IT) | 2019-10-15 | — | — | US | disclosed |
| WO-2017136943-A1 | SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME | CDRD VENTURES INC. (CA) | 2017-08-17 | — | — | WO | disclosed |
| WO-2016046759-A2 | COMPOSITIONS AND METHODS FOR TREATING FRIEDREICH'S ATAXIA | FRATAGENE THERAPEUTICS LTD. (IT) | 2016-03-31 | — | — | WO | disclosed |
| EP-2407460-B1 | N-TRIAZINYLAMMONIUM SALTS, A METHOD OF PREPARATION AND USES THEREOF | POLITECHNIKA LODZKA (PL) | 2013-07-17 | — | — | EP | disclosed |
| US-8420291-B2 | Positive photosensitive resin composition, method for forming pattern, electronic component | HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120094038-A1 | USE OF HUMIDITY STABLE YELLOW FLUORESCENT PIGMENTS IN SECURITY APPLICATIONS | HONEYWELL INTERNATIONAL INC. (US) | 2012-04-19 | — | — | US | disclosed |
| EP-2407460-A1 | N-Triazinylammonium salts, a method of preparation and uses thereof | Politechnika Lódzka (PL) | 2012-01-18 | — | — | EP | disclosed |
| US-20100258336-A1 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR FORMING PATTERN, ELECTRONIC COMPONENT | HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20070141630-A1 | IDENTIFICATION OF NON-COVALENT COMPLEXES BY MASS SPECTROMETRY | GENENTECH, INC. (US) | 2007-06-21 | — | — | US | disclosed |
| US-20070141630-A1 | IDENTIFICATION OF NON-COVALENT COMPLEXES BY MASS SPECTROMETRY | GENENTECH, INC. (US) | 2007-06-21 | — | — | US | disclosed |
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442779-B2 | Compositions and methods for treating Friedreich's ataxia | ATXN10, ATXN2, ATXN2L | NPC1 2715/4885RAB9A 3063/4885SMN1; SMN2 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.