Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 1.00 |
| ▸ | RAB9A | P51151 | 14/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.86 |
| ▸ | TP53 | P04637 | 5/20 | 0.86 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.68 |
| ▸ | RELA | Q04206 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330082 | 1.00 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL6799157 | 0.93 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL8769709 | 0.88 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL8770881 | 0.88 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL6361263 | 0.88 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL30341896 | 0.88 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL22192206 | 0.88 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL22495349 | 0.87 | RAB9A (0.81) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL11911277 | 0.87 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL12228183 | 0.87 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10959984-B2 | Methods for treating cancer with RORγ inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-03-30 | — | — | US | disclosed |
| US-20180085348-A1 | METHODS FOR TREATING CANCER WITH RORGAMMA INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-03-29 | — | — | US | disclosed |
| EP-1885759-B1 | THERMALLY REACTIVE NEAR-INFRARED ABSORBING ACETAL COPOLYMERS, METHODS OF PREPARATION AND METHODS OF USE | AMERICAN DYE SOURCE INC (CA) | 2013-01-23 | — | — | EP | disclosed |
| US-7473515-B2 | Thermally reactive near-infrared absorbing acetal copolymers, methods of preparation and methods of use | AMERICAN DYE SOURCE, INC. (CA) | 2009-01-06 | — | — | US | disclosed |
| US-7473515-B2 | Thermally reactive near-infrared absorbing acetal copolymers, methods of preparation and methods of use | AMERICAN DYE SOURCE, INC. (CA) | 2009-01-06 | — | — | US | disclosed |
| US-20070141630-A1 | IDENTIFICATION OF NON-COVALENT COMPLEXES BY MASS SPECTROMETRY | GENENTECH, INC. (US) | 2007-06-21 | — | — | US | disclosed |
| US-20070141630-A1 | IDENTIFICATION OF NON-COVALENT COMPLEXES BY MASS SPECTROMETRY | GENENTECH, INC. (US) | 2007-06-21 | — | — | US | disclosed |
| WO-2007003030-A1 | THERMALLY REACTIVE NEAR-INFRARED ABSORBING ACETAL COPOLYMERS, METHODS OF PREPARATION AND METHODS OF USE | AMERICAN DYE SOURCE INC. (CA) | 2007-01-11 | — | — | WO | disclosed |
| EP-0620122-B1 | Thermosensitive recording material | NEW OJI PAPER CO LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5446010-A | Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability | NEW OJI PAPER CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0620122-A1 | Thermosensitive recording material | NEW OJI PAPER CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085348-A1 | METHODS FOR TREATING CANCER WITH RORGAMMA INHIBITORS | RORB, RORA, RORC | NPC1 2297/4885RAB9A 2516/4885SMN1; SMN2 4478/4885 |
| US-10959984-B2 | Methods for treating cancer with RORγ inhibitors | RORB, RORC, RORA | NPC1 1579/4885RAB9A 3722/4885SMN1; SMN2 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.