Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 19/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300849 | 1.00 | BACE1 (0.54) | BACE1KCNH2BACE2CYP2D6 | |
| SCHEMBL7916594 | 0.88 | BACE1 (0.52) | BACE1KCNH2BACE2CYP2D6 | |
| SCHEMBL7924984 | 0.88 | BACE1 (0.52) | BACE1KCNH2BACE2CYP2D6 | |
| SCHEMBL3306823 | 0.87 | BACE1 (0.58) | BACE1KCNH2BACE2CYP2D6 | |
| SCHEMBL3298619 | 0.86 | BACE1 (0.58) | BACE1KCNH2BACE2CYP2D6 | |
| SCHEMBL3298112 | 0.86 | BACE1 (0.56) | BACE1KCNH2BACE2CYP2D6 | |
| SCHEMBL19859360 | 0.84 | BACE1 (0.52) | BACE1KCNH2BACE2CYP2D6 | |
| SCHEMBL19868229 | 0.84 | BACE1 (0.52) | BACE1KCNH2BACE2CYP2D6 | |
| SCHEMBL11022485 | 0.84 | BACE1 (0.49) | BACE1BACE2 | |
| SCHEMBL16649518 | 0.83 | BACE1 (0.59) | BACE1KCNH2BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503235-B1 | Polyamide and polyesteramide based on trimerised fatty acids-process of production and application for glues | WITCO GMBH (DE) | 1996-09-11 | — | — | EP | claimed |
| CN-118147094-A | Protein capable of catalyzing monoamidation of symmetrical diamine and derived from fungi and application | 上海交通大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-118142347-A | Preparation method of aliphatic positive nanofiltration membrane based on polyamine diacid chloride monomer | 中国石油大学(华东) | 2024-06-07 | — | — | CN | disclosed |
| US-11981827-B2 | Waterborne polyurethane dispersion and method for preparing the same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-05-14 | — | — | US | disclosed |
| EP-3935098-B1 | WATERBORNE POLYURETHANE DISPERSION AND METHOD FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-11-22 | — | — | EP | disclosed |
| CN-116693863-A | Reticular anti-droplet triazine macromolecule flame-retardant charring agent and preparation method and application thereof | 上海力道新材料科技股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-113631616-B | Aqueous polyurethane dispersion and method for producing same | 陶氏环球技术有限责任公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-115090130-B | Nanofiltration membrane containing silica gel nanoparticle intermediate layer and preparation method thereof | 浙江美易膜科技有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-112045555-B | Method and apparatus for forming advanced polishing pads using additive manufacturing processes | 应用材料公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-112045557-B | Method and apparatus for forming advanced polishing pads using additive manufacturing processes | 应用材料公司 | 2022-11-01 | — | — | CN | disclosed |
| US-20070275911-A1 | Targeted Drug-Formaldehyde Conjugates and Methods of Making and Using the Same | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2007-11-29 | — | — | US | disclosed |
| WO-2005034856-A2 | TARGETED DRUG-FORMALDEHYDE CONJUGATES AND METHODS OF MAKING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2005-04-21 | — | — | WO | disclosed |
| EP-1322626-A1 | PROCESS FOR PREPARATION OF N-1 PROTECTED N RING NITROGEN CONTAINING CYCLIC POLYAMINES AND PRODUCTS THEREOF | ANORMED INC. (CA) | 2003-07-02 | — | — | EP | disclosed |
| US-6489472-B2 | HAS ANTI-HIV (HUMAN IMMUNE DEFICIENCY VIRUS) ACTIVITY | ANORMED, INC. (CA) | 2002-12-03 | — | — | US | disclosed |
| US-20020058807-A1 | Process for preparation of N-1 protected N ring nitrogen containing cyclic polyamines and products thereof | GENZYME CORPORATION | 2002-05-16 | — | — | US | disclosed |
| WO-2002026721-A1 | PROCESS FOR PREPARATION OF N-1 PROTECTED N RING NITROGEN CONTAINING CYCLIC POLYAMINES AND PRODUCTS THEREOF | ANORMED INC. (CA) | 2002-04-04 | — | — | WO | disclosed |
| WO-1991010691-A1 | CURATIVE FOR STRUCTURAL URETHANE ADHESIVE | ASHLAND OIL, INC. (US) | 1991-07-25 | — | — | WO | disclosed |
| US-5002806-A | Polyol, slow and fast reacting polyamines; fiberglass reinforced polyester substrates | ASHLAND OIL, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0382236-A2 | Polyamide laminated on thermoplastic polyurethane | THE B.F. GOODRICH COMPANY (US) | 1990-08-16 | — | — | EP | disclosed |
| US-3956329-A | CRACKING CYCLIZATION | SHUNAN PETROCHEMICAL COMPANY, LTD. (JA) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058807-A1 | Process for preparation of N-1 protected N ring nitrogen containing cyclic polyamines and products thereof | NGLY1, MNS1, SRM | BACE1 2059/4885KCNH2 1549/4885BACE2 4130/4885 |
| US-20070275911-A1 | Targeted Drug-Formaldehyde Conjugates and Methods of Making and Using the Same | HCAR1, DHFR, FOLR1 | BACE1 2939/4885KCNH2 4691/4885BACE2 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.