Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.72 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590638 | 0.86 | NFE2L2 (0.61) | NFE2L2CYP1A1CYP1A2CYP1B1CYP19A1 | |
| SCHEMBL3241394 | 0.84 | NFE2L2 (0.68) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1603723 | 0.84 | NFE2L2 (1.00) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL5500710 | 0.84 | NFE2L2 (1.00) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9185706 | 0.81 | CYP1A1 (0.74) | NFE2L2CYP1A1CYP1A2CYP1B1CYP19A1 | |
| SCHEMBL118591 | 0.78 | NFE2L2 (0.79) | NFE2L2CYP1A1CYP1A2CYP1B1CYP19A1 | |
| Phenol SCHEMBL16930394 | 0.77 | NFE2L2 (0.85) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL615385 | 0.77 | NFE2L2 (0.77) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL8923377 | 0.76 | NFE2L2 (0.52) | NFE2L2TRPA1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1546324 | 0.76 | NFE2L2 (0.59) | NFE2L2CYP1A1CYP1A2CYP1B1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | claimed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | claimed |
| JP-5331185-A | — | — | None | — | — | JP | disclosed |
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | disclosed |
| EP-1504049-B1 | MONOMERS CONTAINING POLYOXYALKYLENES AND POLYMER SUPPORTS THEREFROM | NITTO DENKO AVECIA INC (US) | 2013-05-22 | — | — | EP | disclosed |
| EP-1501851-B1 | PROCESS FOR PREPARING OLIGONUCLEOTIDES | NITTO DENKO AVECIA INC (US) | 2013-02-13 | — | — | EP | disclosed |
| US-8299072-B2 | Pyrazolylmethylamine compounds as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-10-30 | — | — | US | disclosed |
| US-20100094006-A1 | NOVEL PYRAZOLYLMETHYLAMINE COMPOUNDS AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-04-15 | — | — | US | disclosed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | disclosed |
| US-7476709-B2 | Process for preparing oligonucleotides | AVECIA BIOTECHNOLOGY INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-7365132-B2 | Monomers containing polyoxyalkylenes and polymer supports therefrom | AVECIA BIOTECHNOLOGY INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-20060036028-A1 | Process for preparing oligonucleotides | NITTO DENKO AVECIA, INC. | 2006-02-16 | — | — | US | disclosed |
| US-20050256283-A1 | Monomers containing polyoxyalkylenes and polymer supports therefrom | NITTO DENKO AVECIA, INC. | 2005-11-17 | — | — | US | disclosed |
| JP-H05331185-A | 3'-END-LABELFOR NUCLEIC ACID RNA | NIPPON MILLIPORE KOGYO KK | 1993-12-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036028-A1 | Process for preparing oligonucleotides | RTCB, POLRMT, POLM | NFE2L2 1641/4885TRPA1 4654/4885CYP1A1 2742/4885 |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1B, CACNA1C, ORAI1 | NFE2L2 3063/4885TRPA1 66/4885CYP1A1 3819/4885 |
| US-20100094006-A1 | NOVEL PYRAZOLYLMETHYLAMINE COMPOUNDS AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1I, CACNA1C, ORAI1 | NFE2L2 3204/4885TRPA1 52/4885CYP1A1 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.