Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.66 |
| ▸ | MYC | P01106 | 1/20 | 0.59 |
| ▸ | MAX | P61244 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 10/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.58 |
| ▸ | LMNA | P02545 | 10/20 | 0.58 |
| ▸ | HTT | P42858 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | QPCT | Q16769 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300407 | 0.88 | ALDH1A1 (0.54) | MAPTALDH1A1ALOX12PPARGNCOA3 | |
| SCHEMBL3304422 | 0.86 | MYC (0.67) | MAPTALDH1A1ALOX12PPARGNCOA3 | |
| SCHEMBL8164838 | 0.86 | LMNA (0.57) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3300939 | 0.83 | MAPT (0.79) | MAPTALDH1A1ALOX12MYCMAX | |
| SCHEMBL3305997 | 0.80 | MYC (0.74) | MAPTALDH1A1ALOX12MYCMAX | |
| SCHEMBL3302805 | 0.78 | MYC (0.67) | MAPTALDH1A1ALOX12MYCMAX | |
| SCHEMBL4555022 | 0.76 | MAPT (0.67) | MAPTALDH1A1MYCMAXMEN1 | |
| SCHEMBL3297435 | 0.75 | MAPT (0.64) | MAPTALDH1A1ALOX12MYCMAX | |
| SCHEMBL2161427 | 0.74 | MYC (0.61) | MAPTALDH1A1MYCMAXMEN1 | |
| SCHEMBL3299625 | 0.74 | MYC (1.00) | MAPTALDH1A1ALOX12MYCMAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093864-A1 | ANTI-INFECTIVE THIOUREA COMPOUNDS | LICA PHARMACEUTICALS (DK) | 2010-04-15 | — | — | US | disclosed |
| US-20100093864-A1 | ANTI-INFECTIVE THIOUREA COMPOUNDS | LICA PHARMACEUTICALS (DK) | 2010-04-15 | — | — | US | disclosed |
| US-20100093864-A1 | ANTI-INFECTIVE THIOUREA COMPOUNDS | LICA PHARMACEUTICALS (DK) | 2010-04-15 | — | — | US | disclosed |
| EP-2074085-A2 | ANTI-INFECTIVE THIOUREA COMPOUNDS | Lica Pharmaceuticals A/S (DK) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008043840-A2 | ANTI-INFECTIVE THIOUREA COMPOUNDS | LICA PHARMACEUTICALS (DK) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008043840-A2 | ANTI-INFECTIVE THIOUREA COMPOUNDS | LICA PHARMACEUTICALS (DK) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093864-A1 | ANTI-INFECTIVE THIOUREA COMPOUNDS | TST, TPX2, TPMT | MAPT 4691/4885ALDH1A1 4109/4885ALOX12 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.