SCHEMBL3301759

SCHEMBL3301759

CCCCc1cc(CCCC)cc([SiH](O[SiH](c2cc(CCCC)cc(CCCC)c2)c2cc(CCCC)cc(CCCC)c2)c2cc(CCCC)cc(CCCC)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.44
NPC1 O15118 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
PTGS2 P35354 4/20 0.41
CYP3A4 P08684 1/20 0.41
GPR84 Q9NQS5 2/20 0.40
SKP2 Q13309 1/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 1/20 0.36
RARB P10826 1/20 0.34
FUT7 Q11130 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3293298 0.81 LPL (0.44) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL3300363 0.79 CA2 (0.47) HPGDPTGS2CYP3A4CA1CA2
SCHEMBL2002090 0.79 HPGD (0.61) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL27994037 0.77 HPGD (0.58) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL3298696 0.76 NPC1 (0.41) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL6534660 0.74 HPGD (0.56) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL28161119 0.72 HPGD (0.54) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL1187465 0.72 HPGD (0.54) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL2871788 0.71 PTGS2 (0.68) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL27887331 0.71 PTGS2 (0.53) PTGS2CYP3A4GPR84FUT7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741393-B2 Organic silicon-based compound and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same ARSA, OR10J3, HDAC10 HPGD 4795/4885NPC1 2062/4885MAPK1 1006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.