Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 4/20 | 0.53 |
| ▸ | S100A4 | P26447 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306550 | 0.84 | TTR (0.61) | TTRPTPRCS100A4HTR7HTR2B | |
| SCHEMBL3302191 | 0.83 | TTR (0.49) | TTRPTPRCS100A4HTR7HTR2B | |
| SCHEMBL13390037 | 0.80 | NPC1 (0.46) | TTRPTPRCS100A4HTR7HTR2B | |
| SCHEMBL4921071 | 0.78 | TTR (0.61) | TTRPTPRCS100A4HTR7HTR2B | |
| SCHEMBL11839301 | 0.77 | KEAP1 (0.56) | TTRPTPRCS100A4HTR7HTR2B | |
| SCHEMBL4455730 | 0.77 | SRD5A2 (0.59) | HTR7HTR2BNPC1RAB9AATM | |
| SCHEMBL2265496 | 0.76 | TTR (0.62) | TTRPTPRCS100A4HTR7HTR2B | |
| SCHEMBL8014885 | 0.75 | S100A4 (0.86) | TTRPTPRCS100A4HTR7HTR2B | |
| SCHEMBL31268599 | 0.75 | S100A4 (0.86) | TTRPTPRCS100A4HTR7HTR2B | |
| SCHEMBL13705055 | 0.75 | ADORA2A (0.60) | TTRPTPRCS100A4HTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093883-A1 | Hydroxamic Esters as Photoinitiators | LAMBERTI SPA (IT) | 2010-04-15 | — | — | US | disclosed |
| US-20100093883-A1 | Hydroxamic Esters as Photoinitiators | LAMBERTI SPA (IT) | 2010-04-15 | — | — | US | disclosed |
| US-20100093883-A1 | Hydroxamic Esters as Photoinitiators | LAMBERTI SPA (IT) | 2010-04-15 | — | — | US | disclosed |
| EP-2121323-A1 | HYDROXAMIC ESTERS AS PHOTOINITIATORS | Lamberti Spa (IT) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008104436-A1 | HYDROXAMIC ESTERS AS PHOTOINITIATORS | LAMBERTI SPA (IT) | 2008-09-04 | — | — | WO | disclosed |