Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634211 | 0.91 | SLC18A3 (0.49) | DGAT1SLC18A3HTR2BNAMPTALDH1A1 | |
| SCHEMBL3304712 | 0.88 | HPGD (0.55) | SLC18A3HTR2BALDH1A1TDP1HPGD | |
| SCHEMBL3303476 | 0.86 | PARP10 (0.48) | DGAT1HTR2BNAMPTESR2HPGD | |
| SCHEMBL3810068 | 0.85 | SLC18A3 (0.54) | DGAT1SLC18A3HTR2BNAMPTALDH1A1 | |
| SCHEMBL3297763 | 0.84 | HTT (0.53) | HTR2BNAMPTTDP1CNR1 | |
| SCHEMBL3809829 | 0.82 | SLC18A3 (0.51) | DGAT1SLC18A3HTR2BNAMPT | |
| SCHEMBL520567 | 0.81 | NAMPT (0.55) | SLC18A3NAMPTSMYD3 | |
| SCHEMBL3816677 | 0.81 | SLC18A3 (0.46) | DGAT1SLC18A3HTR2BNAMPT | |
| SCHEMBL3668526 | 0.78 | HTR2B (0.49) | DGAT1SLC18A3HTR2BNAMPTSMYD3 | |
| SCHEMBL6906434 | 0.77 | ESR2 (0.65) | DGAT1SLC18A3ESR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093733-A1 | AMIDE AND UREA DERIVATIVES FOR THE TREATMENT OF METABOLIC DISEASES | PROSIDION LIMITED (GB) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093733-A1 | AMIDE AND UREA DERIVATIVES FOR THE TREATMENT OF METABOLIC DISEASES | CPS1, GOT2, GPR119 | DGAT1 84/4885SLC18A3 3159/4885HTR2B 3738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.