Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676977 | 1.00 | HAO1 (0.42) | HAO1HTR2CHTR2BRORCLMNA | |
| SCHEMBL676292 | 0.98 | HDAC8 (0.41) | HAO1HTR2CHTR2BRORCLMNA | |
| SCHEMBL2919141 | 0.93 | ESR2 (0.43) | HAO1HTR2CHTR2BRORCMITF | |
| SCHEMBL2923249 | 0.89 | ESR2 (0.42) | — | |
| SCHEMBL5544467 | 0.83 | SPHK1 (0.40) | HAO1HTR2CHTR2BLMNAHTT | |
| SCHEMBL9643569 | 0.83 | HAO1 (0.42) | HAO1HTR2CHTR2BRORCLMNA | |
| SCHEMBL4452070 | 0.82 | LTA4H (0.44) | HAO1HTR2CHTR2BLMNAHTT | |
| SCHEMBL3146239 | 0.81 | SPHK1 (0.41) | HAO1HTR2CHTR2BLMNAMAPT | |
| SCHEMBL15260520 | 0.81 | HDAC8 (0.52) | HAO1LMNAHTTMAPTHDAC8 | |
| SCHEMBL6275125 | 0.81 | HDAC8 (0.52) | HAO1LMNAHTTMAPTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260834-A | Sulfur-containing high-refractive-index ink composition and preparation method thereof | 西安思摩威新材料有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-110117428-B | Flexible organic packaging composition and preparation and use method thereof | 西安思摩威新材料有限公司 | 2021-04-20 | — | — | CN | claimed |
| EP-2407511-B1 | Thermoplastic resin composition | CHEIL IND INC (KR) | 2017-03-22 | — | — | EP | claimed |
| CN-102250458-B | Poly carbonate resin composition and moulded product thereof | CHEIL INDUSTRIES INC. (KR) | 2016-01-27 | — | — | CN | claimed |
| US-8557912-B2 | Thermoplastic resin composition | CHEIL INDUSTRIES INC. (KR) | 2013-10-15 | — | — | US | claimed |
| EP-2582409-A1 | HIGH REFRACTIVE INDEX, ACRYLIC OPHTHALMIC DEVICE MATERIALS WITH REDUCED GLISTENINGS | Novartis AG (CH) | 2013-04-24 | — | — | EP | claimed |
| US-20120016068-A1 | Thermoplastic Resin Composition | CHEIL INDUSTRIES INC. (KR) | 2012-01-19 | — | — | US | claimed |
| EP-2407511-A1 | Thermoplastic resin composition | Cheil Industries Inc. (KR) | 2012-01-18 | — | — | EP | claimed |
| WO-2011163126-A1 | HIGH REFRACTIVE INDEX, ACRYLIC OPHTHALMIC DEVICE MATERIALS WITH REDUCED GLISTENINGS | NOVARTIS AG (CH) | 2011-12-29 | — | — | WO | claimed |
| CN-102250458-A | Polycarbonate resin composition and molded product using the same | CHEIL IND INC | 2011-11-23 | — | — | CN | claimed |
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | claimed |
| US-6699855-B2 | PYRROLOPYRAZINONES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2004-03-02 | — | — | US | claimed |
| EP-1177227-B1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORP (US) | 2003-10-01 | — | — | EP | claimed |
| US-20020128417-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2002-09-12 | — | — | US | claimed |
| US-20020065248-A1 | Inhibitors of hepatitis C virus NS3 protease | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-05-30 | — | — | US | claimed |
| EP-1177227-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2002-02-06 | — | — | EP | claimed |
| US-20020007032-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2002-01-17 | — | — | US | claimed |
| US-20010056165-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2001-12-27 | — | — | US | claimed |
| US-6281319-B1 | HYDRATABLE POLYMER | SURGIDEV CORPORATION | 2001-08-28 | — | — | US | claimed |
| WO-2000061646-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2000-10-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065248-A1 | Inhibitors of hepatitis C virus NS3 protease | TMPRSS15, CTRC, CPN1 | HAO1 3464/4885HTR2C 1247/4885HTR2B 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.