SCHEMBL3303880

SCHEMBL3303880

CC(=O)ON(C)C(=O)c1ccc(N(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
HPGD P15428 5/20 0.53
MAPT P10636 3/20 0.53
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 5/20 0.47
RAB9A P51151 4/20 0.47
MAPK1 P28482 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HDAC6 Q9UBN7 3/20 0.44
HDAC8 Q9BY41 1/20 0.44
POLB P06746 2/20 0.43
HDAC1 Q13547 2/20 0.43
TSHR P16473 3/20 0.42
ALOX15 P16050 2/20 0.42
CYP3A4 P08684 1/20 0.42
HBB P68871 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA2 P00918 1/20 0.41
HSD17B10 Q99714 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13479711 0.81 ALOX15 (0.46) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL3305455 0.81 ALDH1A1 (0.57) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL13604121 0.81 HSD11B1 (0.46) ALDH1A1HPGDMEN1KMT2ANPC1
SCHEMBL3305642 0.81 ALDH1A1 (0.48) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL3304137 0.81 ALDH1A1 (0.48) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL13390431 0.78 ALDH1A1 (0.46) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL13479810 0.77 NSD2 (0.48) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL3303480 0.77 ALDH1A1 (0.44) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL8816853 0.76 HDAC1 (0.54) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL27770144 0.76 HDAC3 (0.47) ALDH1A1HPGDMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100093883-A1 Hydroxamic Esters as Photoinitiators LAMBERTI SPA (IT) 2010-04-15 US disclosed
US-20100093883-A1 Hydroxamic Esters as Photoinitiators LAMBERTI SPA (IT) 2010-04-15 US disclosed
US-20100093883-A1 Hydroxamic Esters as Photoinitiators LAMBERTI SPA (IT) 2010-04-15 US disclosed
EP-2121323-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS Lamberti Spa (IT) 2009-11-25 EP disclosed
WO-2008104436-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS LAMBERTI SPA (IT) 2008-09-04 WO disclosed