SCHEMBL330390

SCHEMBL330390

Nc1cc(C(F)(F)F)ccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
KDM4E B2RXH2 3/20 0.50
TSHR P16473 3/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TP53 P04637 1/20 0.50
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
MAPT P10636 2/20 0.46
GAA P10253 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
GFER P55789 1/20 0.46
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4373948 0.98 ALDH1A1 (0.48) ALDH1A1KDM4ETSHRPKMHPGD
Hydrochloric Acid SCHEMBL27454522 0.98 ALDH1A1 (0.48) ALDH1A1KDM4ETSHRPKMHPGD
SCHEMBL31053156 0.82 CYP3A4 (0.50) ALDH1A1KDM4ETSHRPKMHPGD
SCHEMBL119351 0.82 CYP3A4 (0.50) ALDH1A1KDM4ETSHRPKMHPGD
SCHEMBL7877357 0.80 TSHR (0.48) ALDH1A1KDM4ETSHRPKMTP53
Hydrochloric Acid SCHEMBL6862385 0.80 ALDH1A1 (0.52) ALDH1A1KDM4ETSHRPKMHPGD
SCHEMBL24751491 0.79 L3MBTL1 (0.46) TSHRTP53CA1CA2CA9
SCHEMBL31694836 0.79 L3MBTL1 (0.46) TSHRTP53CA1CA2CA9
SCHEMBL980201 0.78 TSHR (0.61) ALDH1A1TSHRTP53L3MBTL1MAPT
SCHEMBL29402881 0.78 TSHR (0.61) ALDH1A1TSHRTP53L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 854 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4423162-A1 REACTION INDUCED COLOR-CHANGE COMPOSITION Zephyros, Inc. (US) 2024-09-04 EP claimed
CN-118176229-A Reaction-induced color-changing composition 泽菲罗斯有限公司 2024-06-11 CN claimed
WO-2023076650-A1 REACTION INDUCED COLOR-CHANGE COMPOSITION ZEPHYROS, INC. (US) 2023-05-04 WO claimed
EP-1773768-B1 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2018-08-22 EP claimed
US-9759733-B1 Mass produced, low cost, portable test kit for the detection and identification of narcotics VERITEQUE USA, INC. 2017-09-12 US claimed
US-8916599-B2 1H-benz imidazole-5-carboxamides as anti-inflammatory agents OREXO AB (SE) 2014-12-23 US claimed
EP-1888596-B1 SUBSTITUTED SPIRO COMPOUNDS AND THEIR USE FOR PRODUCING PAIN-RELIEF MEDICAMENTS GRUENENTHAL GMBH (DE) 2014-10-22 EP claimed
EP-2292625-B1 SUBSTITUTED SPIRO COMPOUNDS AND THEIR USE FOR PRODUCING PAIN-RELIEF MEDICAMENTS GRUENENTHAL GMBH (DE) 2013-12-25 EP claimed
CN-102781920-A Process for synthesizing fipronil HORMUSJI GHARDA KEKI 2012-11-14 CN claimed
EP-1506196-B1 PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS ICAGEN INC (US) 2012-01-18 EP claimed
WO-2002042303-A2 ACYL AND SULFONYL DERIVATIVES OF 6,9-DISUBSTITUTED 2-(TRANS-1,4-DIAMINOCYCLOHEXYL)-PURINES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS AVENTIS PHARMACEUTICALS INC. (US) 2002-05-30 WO claimed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
EP-1195411-A1 Process for the preparation of azo colourants Clariant GmbH (DE) 2002-04-10 EP claimed
US-5629449-A REDUCTION OF 4-CHLORO-3,4-DINITROBENZOTRIFLUORIDE OCCIDENTAL CHEMICAL CORPORATION (US) 1997-05-13 US claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed
US-4767757-A Acyloxythiophene-carboxamide fungicides, compositions and use BAYER AKTIENGESELLSCHAFT (DE) 1988-08-30 US claimed
EP-0241735-A2 Acyloxythiophene carbon amide BAYER AG (DE) 1987-10-21 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed